SARS-CoV-2 might directly activate NLRP3 inflammasome resulting in an endogenous
adjuvant activity necessary to mount a proper adaptive immune response against the virus. …

Type III CRISPR-Cas immunity is widespread in prokaryotes and is generally mediated by
multisubunit effector complexes. These complexes recognize complementary viral transcripts …

Transfer RNAs (tRNAs) in bacteriophage genomes are widespread across bacterial host
genera, but their exact function has remained unclear for more than 50 years. Several …

Bacteriophages are an invaluable source of novel genetic diversity. Sequencing of phage
genomes can reveal new proteins with potential uses as biotechnological and medical tools, …

Prokaryotes encode multiple distinct anti-phage defense systems in their genomes. However,
the impact of carrying a multitude of defense systems on phage resistance remains unclear…

The bacterial chromosome is spatially organized through protein-mediated compaction,
supercoiling, and cell-boundary confinement. Structural Maintenance of Chromosomes (SMC) …

Prokaryotes carry multiple distinct anti-viral defense systems. However, the impact of carrying
a multitude of defense systems on virus resistance remains unclear, especially in a clinical …

Serratia sp. ATCC 39006 is a Gram-negative bacterium that has been used to study the function
of phage defences, such as CRISPR–Cas, and phage counter-defence mechanisms. To …

This survey compiles ideas and recommendations from more than a dozen researchers with
different backgrounds and from different institutes around the world. Promoting best practice …

… van den Berg, 2019). Nonetheless, these principles create algorithms that are more
widely applicable, as is so aptly described by Kenneth Sörensen (Sörensen, 2015). Many “novel” …