Deficiency of inflammation‐sensing protein neuropilin‐2 in myeloid‐derived macrophages exacerbates colitis via NF‐κB activation

T Li, J Ran, Z Miao, M Yang, D Mou… - The Journal of …, 2024 - Wiley Online Library
Neuropilin‐2 (NRP2) is a multifunctional protein engaged in the regulation of angiogenesis,
lymphangiogenesis, axon guidance, and tumor metastasis, but its function in colitis remains …

Stat5−/− CD4+ T cells elicit anti-melanoma effect by CD4+ T cell remolding and Notch1 activation

K Jin, T Li, Z Miao, J Ran, L Chen, D Mou… - Science China Life …, 2022 - Springer
Signal transducers and activators of transcription 5 (Stat5) is known to engage in regulating
the differentiation and effector function of various subsets of T helper cells. However, how …

[HTML][HTML] Infant rhesus macaques as a non-human primate model of Bordetella pertussis infection

W Jiang, C Wei, D Mou, W Zuo, J Liang, X Ma… - BMC Infectious …, 2021 - Springer
Background The prevalent resurgence of pertussis has recently become a critical public health
problem worldwide. To understand pertussis pathogenesis and the host response to both …

[HTML][HTML] SIGIRR deficiency contributes to CD4 T cell abnormalities by facilitating the IL1/C/EBPβ/TNF-α signaling axis in rheumatoid arthritis

X Teng, DC Mou, HF Li, L Jiao, SS Wu, JK Pi… - Molecular …, 2022 - Springer
Background Rheumatoid arthritis (RA) is a complex autoimmune disease with multiple
etiological factors, among which aberrant memory CD4 T cells activation plays a key role in the …

Aerosol challenge model in murine by Bordetella pertussis

D Mou, J Liang, N Gao, Q GU, M Zhang… - Journal of Medical …, 2017 - pesquisa.bvsalud.org
Objective To evaluate the BALB/c murine infective effects in different concentrations and
different aerosol challenge times by Bordetella pertussis. Methods Four experiment groups …

YKL-40 Promotes the Expression of Inflammatory Factors in Type Ⅱ Alveolar Epithelial Cell Model of A549 Cell Line

M Zhiyong, RAN Jingjing, MOU Dachao… - JOURNAL OF …, 2023 - ykxb.scu.edu.cn
Objective YKL-40, also known as chitinase-3-like-1 (CHI3L1), is a human cartilage
glycoprotein-39, with its N-terminus consisting of tyrosine (Y), lysine (K), and leucine (L), hence the …

Analysis of Granulocyte-Macrophage Colony-Stimulating Factor-Producing T Helper Cells in a Mouse Model of Contact Hypersensitivity

…, HF Li, XY Ren, L Jiao, SS Wu, DC Mou… - JoVE (Journal of …, 2022 - jove.com
Parallel to traditional Th1/Th2/Th17/Treg lineages, granulocyte-macrophage colony-stimulating
factor-producing T helper (Th-GM) cells have been identified as a distinct subset of T …

ThGM cells as a prognostic and predictive marker for coronary heart disease

D Mou, L Jiao, Y Zhou - 2022 - researchsquare.com
Background Coronary heart disease (CHD) is causing by the aberrant aggregation of immune
cells in plaque. This study aimed to identify abnormal T cell subtypes and inflammatory …

Infant Rhesus Macaques as a Nonhuman Primate Model of Bordetella Pertussis

L Shi, W Jiang, C Wei, D Mou, W Zuo, J Liang, X Ma… - 2020 - researchsquare.com
Background: The prevalent resurgence of pertussis recently creates a vital public health
problem worldwide. To understand the pertussis pathogenesis and host response to both …

Experimental infection characteristics of Bordetella pertussis via aerosol challenge on rhesus macaques

D Mou, P Luo, J Liang, Q Ji, L Wang, N Gao, Q Gu… - bioRxiv, 2018 - biorxiv.org
The effect of aerosol challenge of rhesus macaques with Bordetella pertussis and the feasibility
of using rhesus monkeys as an animal model for pertussis infection were evaluated in …