Global insights into cellular organization and genome function require comprehensive
understanding of the interactome networks that mediate genotype–phenotype relationships 1 , 2 . …

Although archaea, Gram‐negative bacteria, and mammalian cells constitutively secrete
membrane vesicles (MVs) as a mechanism for cell‐free intercellular communication, this cellular …

Secretion of extracellular vesicles is a general cellular activity that spans the range from
simple unicellular organisms (eg archaea; Gram‐positive and Gram‐negative bacteria) to …

Mammalian cells secrete two types of extracellular vesicles either constitutively or in a
regulated manner: exosomes (50–100 nm in diameter) released from the intracellular …

The gut microbiota has an important role in the gut barrier, inflammation and metabolic functions.
Studies have identified a close association between the intestinal barrier and metabolic …

Gut microbiota play an important part in the pathogenesis of mucosal inflammation, such as
inflammatory bowel disease (IBD). However, owing to the complexity of the gut microbiota, …

Almost all bacteria, archaea, and eukaryotic cells shed extracellular vesicles either constitutively
or in a regulated manner. These nanosized membrane vesicles are spherical, bilayered …

Despite exceptional experimental efforts to map out the human interactome, the continued
data incompleteness limits our ability to understand the molecular roots of human disease. …

Motivation: Extracellular vesicles (EVs) are spherical bilayered proteolipids, harboring
various bioactive molecules. Due to the complexity of the vesicular nomenclatures and …

Large oncosomes (LO) are atypically large (1-10μm diameter) cancer-derived extracellular
vesicles (EVs), originating from the shedding of membrane blebs and associated with …