Abstract Analysis of small numbers of chromosomes using interphase fluorescent in-situ
hybridization (FISH) probes has revealed that 50% of human preimplantation embryos contain …

Molecular genetic analysis of isolated single cells and other minute DNA samples is limited
because there is insufficient DNA to perform more than one independent PCR amplification. …

OBJECTIVE: To assess correlation between blastocyst morphology and chromosomal status.
DESIGN: Observational research study. SETTING: An IVF clinic and a specialist …

Objective To evaluate the benefit of next-generation sequencing (NGS)–based preimplantation
genetic testing for aneuploidy (PGT-A) for embryo selection in frozen-thawed embryo …

OBJECTIVE: To evaluate a new strategy for comprehensive chromosome screening at the
blastocyst stage. DESIGN: Clinical research study. SETTING: An IVF clinic and a specialist …

Despite their fundamental biological and clinical importance, the molecular mechanisms that
regulate the first cell fate decisions in the human embryo are not well understood. Here we …

Objective To identify cell types in the male and female reproductive systems at risk for SARS-CoV-2
infection because of the expression of host genes and proteins used by the virus for …

OBJECTIVE: To validate and determine the best array–comparative genomic hybridization (aCGH;
array-CGH) protocols for preimplantation genetic screening (PGS). DESIGN: …

Objective To assess the relationship between maternal age, chromosome abnormality,
implantation, and pregnancy loss. Design Multicenter retrospective study. Setting IVF centers in …

Mitochondria play a vital role in embryo development. They are the principal site of energy
production and have various other critical cellular functions. Despite the importance of this …