Mitochondrial function affects many aspects of cellular physiology, and, most recently, its role
in epigenetics has been reported. Mechanistically, how mitochondrial function alters DNA …

Guanine nucleotide binding (G) proteins (subunit composition αβγ) dissociate on activation
with guanosine triphosphate (GTP) analogs and magnesium to give α-guanine nucleotide …

Because of the use of alternate exons 1, mammals express two distinct forms of Gsα-subunits:
the canonical 394-aa Gsα present in all tissues and a 700+-aa extra-long αs (XLαs) …

The impact of mitochondrial dysfunction in epigenetics is emerging, but our understanding
of this relationship and its effect on gene expression remains incomplete. We previously …

Mitochondrial-driven alterations of the epigenome have been reported, but whether they are
relevant at the organismal level remains unknown. The viable yellow agouti mouse (A vy ) is …

The resolved α‐GTPγS (α*) and βγ‐subunits of human erythrocyte G k , the stimulatory
regulatory component of hormone‐responsive K + channels, were tested for their potential …

ADP ribosylation of membranes by pertussis toxin (PT) and cholera toxin (CT) was studied
as a function of addition of ATP, various guanine nucleotides, Mg 2+ , and inorganic …

In purified preparations of human erythrocyte GTP-binding proteins, we have identified a
new substrate for pertussis toxin, which has an apparent molecular mass of 43 kDa by silver …

We describe an updated and improved protocol to perform urea gradient/SDS-PAGE in which
proteins are electrophoresed through 9% polyacrylamide gel slabs in the presence of a …

PGC1α is a transcriptional coactivator in peripheral tissues, but its function in the brain
remains poorly understood. Various brain-specific Pgc1α isoforms have been reported in mice …