ChAdOx1 interacts with CAR and PF4 with implications for thrombosis with thrombocytopenia syndrome
Vaccines derived from chimpanzee adenovirus Y25 (ChAdOx1), human adenovirus type 26
(HAdV-D26), and human adenovirus type 5 (HAdV-C5) are critical in combatting the severe …
(HAdV-D26), and human adenovirus type 5 (HAdV-C5) are critical in combatting the severe …
Prediction of protein assemblies, the next frontier: The CASP14‐CAPRI experiment
We present the results for CAPRI Round 50, the fourth joint CASP‐CAPRI protein assembly
prediction challenge. The Round comprised a total of twelve targets, including six dimers, …
prediction challenge. The Round comprised a total of twelve targets, including six dimers, …
[HTML][HTML] Cryo-EM model validation recommendations based on outcomes of the 2019 EMDataResource challenge
This paper describes outcomes of the 2019 Cryo-EM Model Challenge. The goals were to (1)
assess the quality of models that can be produced from cryogenic electron microscopy (…
assess the quality of models that can be produced from cryogenic electron microscopy (…
The ugly, bad, and good stories of large-scale biomolecular simulations
Molecular modeling of large biomolecular assemblies exemplifies a disruptive area holding
both promises and contentions. Propelled by peta and exascale computing, several …
both promises and contentions. Propelled by peta and exascale computing, several …
Fermentation-based biotransformation of bioactive phenolics and volatile compounds from cashew apple juice by select lactic acid bacteria
…, O Kerdchoechuen, N Laohakunjit, D Sarkar… - Process …, 2017 - Elsevier
Select lactic acid bacteria (LAB); Lactobacillus plantarum, L. casei and L. acidophilus were
targeted for enhancing bioactives and flavor volatiles of cashew apple juice (CAJ) that is an …
targeted for enhancing bioactives and flavor volatiles of cashew apple juice (CAJ) that is an …
Mechanisms underlying the antihypertensive effects of garlic bioactives
Cardiovascular disease remains the leading cause of death worldwide with hypertension
being a major contributing factor to cardiovascular disease–associated mortality. On a …
being a major contributing factor to cardiovascular disease–associated mortality. On a …
Temperature distribution in multi-layer skin tissue in presence of a tumor
Analytical investigation of bioheat transfer is of significant importance for numerous medical
applications, for example in thermally-driven treatments for cancer. While bioheat transfer …
applications, for example in thermally-driven treatments for cancer. While bioheat transfer …
[PDF][PDF] CryoFold: Determining protein structures and data-guided ensembles from cryo-EM density maps
Cryoelectron microscopy requires molecular modeling for refinement of structures. Ensemble
models arrive at low free-energy molecular structures, but are computationally expensive …
models arrive at low free-energy molecular structures, but are computationally expensive …
Topoisomerase I inhibitors: Challenges, progress and the road ahead
A Talukdar, B Kundu, D Sarkar, S Goon… - European Journal of …, 2022 - Elsevier
Topoisomerase IB (Top1), a subcategory of DNA topoisomerase enzymes is expressed much
higher in several tumor cells. Therefore, modulating the activity of Top1 in tumor cells to …
higher in several tumor cells. Therefore, modulating the activity of Top1 in tumor cells to …
Growth and enzymatic activity of maize (Zea mays L.) plant: Solution culture test for copper dioxide nano particles
T Adhikari, D Sarkar, H Mashayekhi… - Journal of Plant …, 2016 - Taylor & Francis
Copper (Cu) is an essential micronutrient for plants, which acts either as the metal component
of enzymes or as a functional structural or a regulatory co-factor of a large number of …
of enzymes or as a functional structural or a regulatory co-factor of a large number of …