Copy number variation (CNV) of DNA sequences is functionally significant but has yet to be
fully ascertained. We have constructed a first-generation CNV map of the human genome …

Abundant accumulation of digital histopathological images has led to the increased demand
for their analysis, such as computer-aided diagnosis using machine learning techniques. …

Automated detection of cancer metastases in lymph nodes has the potential to improve the
assessment of prognosis for patients. To enable fair comparison between the algorithms for …

Gastric cancer is among the most common malignancies worldwide, characterized by
geographical, epidemiological and histological heterogeneity. Here, we report an extensive, …

Recent reports indicate that copy number variations (CNVs) within the human genome
contribute to nucleotide diversity to a larger extent than single nucleotide polymorphisms (SNPs). …

Genome-wide studies reveal that transcription by RNA polymerase II (Pol II) is dynamically
regulated. To obtain a comprehensive view of a single transcription cycle, we switched on …

Infection with CagA-producing Helicobacter pylori plays a causative role in the development
of gastric cancer. Upon delivery into gastric epithelial cells, CagA deregulates prooncogenic …

Abstract Machine learning techniques, especially deep learning techniques such as convolutional
neural networks, have been successfully applied to general image recognitions since …

YAP 1, the main Hippo pathway effector, is a potent oncogene and is overexpressed in non‐small‐cell
lung cancer ( NSCLC ); however, the YAP 1 expression pattern in small‐cell lung …

Overexpression of periostin (POSTN), an extracellular matrix protein, has been observed in
several cancers. We investigated the importance of POSTN in gastric cancer. Genome-wide …