Ligand-gated ion channels: new insights into neurological disorders and ligand recognition

D Lemoine, R Jiang, A Taly, T Chataigneau… - Chemical …, 2012 - ACS Publications
1. INTRODUCTION Ligand-gated ion channels (LGICs) mediate intercellular communication
by converting the binding of a neurotransmitter that is released from the presynaptic …

Mechanisms of xylem recovery from winter embolism in Fagus sylvatica

H Cochard, D Lemoine, T Améglio, A Granier - Tree Physiology, 2001 - academic.oup.com
Hydraulic conductivity in the terminal branches of mature beech trees (Fagus sylvatica L.)
decreased progressively during winter and recovered in the spring. The objective of this study …

Plant ontogeny and chemical defence: older seedlings are better defended

A Elger, DG Lemoine, M Fenner, ME Hanley - Oikos, 2009 - Wiley Online Library
Although patterns of seedling selection by herbivores are strongly influenced by plant age and
the expression of anti‐herbivore defence, it is unclear how these characteristics interact to …

Within crown variation in hydraulic architecture in beech (Fagus sylvatica L): evidence for a stomatal control of xylem embolism

D Lemoine, H Cochard, A Granier - Annals of forest science, 2002 - afs-journal.org
The stomatal control of embolism in Fagus sylvatica L. was analysed in response to crown
position and experimental changes of trunk hydraulic resistance. On one mature beech tree …

Tightening of the ATP‐binding sites induces the opening of P2X receptor channels

R Jiang, A Taly, D Lemoine, A Martz, O Cunrath… - The EMBO …, 2012 - embopress.org
The opening of ligand‐gated ion channels in response to agonist binding is a fundamental
process in biology. In ATP‐gated P2X receptors, little is known about the molecular events …

[HTML][HTML] Exploring the ATP-binding site of P2X receptors

T Chataigneau, D Lemoine, T Grutter - Frontiers in cellular …, 2013 - frontiersin.org
P2X receptors are ATP-gated non-selective cation channels involved in many different
physiological processes, such as synaptic transmission, inflammation, and neuropathic pain. …

Optical control of an ion channel gate

D Lemoine, C Habermacher, A Martz… - Proceedings of the …, 2013 - National Acad Sciences
The powerful optogenetic pharmacology method allows the optical control of neuronal activity
by photoswitchable ligands tethered to channels and receptors. However, this approach is …

Manipulating midbrain dopamine neurons and reward-related behaviors with light-controllable nicotinic acetylcholine receptors

R Durand-de Cuttoli, S Mondoloni, F Marti, D Lemoine… - Elife, 2018 - elifesciences.org
10.7554/eLife.37487.001 Dopamine (DA) neurons of the ventral tegmental area (VTA)
integrate cholinergic inputs to regulate key functions such as motivation and goal-directed …

Mechanism of freeze-induced embolism in Fagus sylvatica L.

D Lemoine, A Granier, H Cochard - Trees, 1999 - Springer
The mechanism of freeze stress-induced embolism in Fagus sylvatica L. branches was
analyzed under controlled conditions. Excised branches were exposed to successive freeze-…

Determinants of macrophyte palatability to the pond snail Lymnaea stagnalis

A Elger, D Lemoine - Freshwater Biology, 2005 - Wiley Online Library
This study aimed to identify the chemical and structural determinants of macrophyte palatability
to the pond snail Lymnaea stagnalis. Eleven macrophyte species were investigated, and …