The centromere is the chromosomal locus that ensures fidelity in genome transmission at cell
division. Centromere protein A (CENP-A) is a histone H3 variant that specifies centromere …

Histone variants are key players in shaping chromatin structure, and, thus, in regulating
fundamental cellular processes such as chromosome segregation and gene expression. …

Context: Psychosocial exposures commonly show large variation over time and are usually
assessed using multi-item Likert indices. A construct requiring a five-item Likert index could …

Background The aim of the present study was to assess possible effects on mental and physical
well-being and stress-related biological markers of a web-based health promotion tool. …

A growing trend among clinical studies is the use of heart rate monitors (HRMs) for
assessment of heart rate variability (HRV). These instruments offer a convenient alternative to …

The chromatin template imposes an epigenetic barrier during the process of somatic cell
reprogramming. Using fibroblasts derived from macroH2A double knockout (dKO) mice, here …

Histone variants are emerging as key regulatory molecules in cancer. We report a unique
role for the H2A.Z isoform H2A.Z.2 as a driver of malignant melanoma. H2A.Z.2 is highly …

Background Current human and experimental studies are indicating an association between
stress and hearing problems; however potential risk factors have not been established. …

Background Tandemly Repeated DNA represents a large portion of the human genome,
and accounts for a significant amount of copy number variation. Here we present a genome …

The histone variant macroH2A generally associates with transcriptionally inert chromatin;
however, the factors that regulate its chromatin incorporation remain elusive. Here, we identify …