Exosomes in development, metastasis and drug resistance of breast cancer

D Yu, Y Wu, H Shen, M Lv, W Chen, X Zhang… - Cancer …, 2015 - Wiley Online Library
Transport through the cell membrane can be divided into active, passive and vesicular types
(exosomes). Exosomes are nano‐sized vesicles released by a variety of cells. Emerging …

[HTML][HTML] SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target

…, Y Zhou, X Cheng, X Xin, L Jin, HL Zhang, DD Yu… - Cell research, 2021 - nature.com
Cytokine storm and multi-organ failure are the main causes of SARS-CoV-2-related death.
However, the origin of excessive damages caused by SARS-CoV-2 remains largely unknown. …

[HTML][HTML] The role of autophagy induced by tumor microenvironment in different cells and stages of cancer

X Yang, DD Yu, F Yan, YY Jing, ZP Han, K Sun… - Cell & bioscience, 2015 - Springer
Abstract Development of a tumor is a very complex process, and invasion and metastasis of
malignant tumors are hallmarks and are difficult problems to overcome. The tumor …

Exosomes from adriamycin-resistant breast cancer cells transmit drug resistance partly by delivering miR-222

D Yu, Y Wu, X Zhang, M Lv, W Chen, X Chen, S Yang… - Tumor Biology, 2016 - Springer
Breast cancer (BCa) is one of the major deadly cancers in women. However, treatment of BCa
is still hindered by the acquired-drug resistance. It is increasingly reported that exosomes …

[HTML][HTML] COVID-19-like symptoms observed in Chinese tree shrews infected with SARS-CoV-2

L Xu, DD Yu, YH Ma, YL Yao, RH Luo… - Zoological …, 2020 - ncbi.nlm.nih.gov
The coronavirus disease 2019 (COVID-19) pandemic continues to pose a global threat to
the human population. Identifying animal species susceptible to infection with the SARS-CoV-2…

[HTML][HTML] Interferon-armed RBD dimer enhances the immunogenicity of RBD for sterilizing immunity against SARS-CoV-2

…, F Zhao, S Zhang, Y Gao, JB Han, XL Feng, DD Yu… - Cell Research, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a global crisis,
urgently necessitating the development of safe, efficacious, convenient-to-store, and low-…

Toll like receptor 4 facilitates invasion and migration as a cancer stem cell marker in hepatocellular carcinoma

WT Liu, YY Jing, G Yu, Z Han, D Yu, QM Fan, F Ye, R Li… - Cancer letters, 2015 - Elsevier
Cancer stem cells (CSCs) or tumor-initiating cells (TICs), a small subset of tumor cells, are
involved in tumor initiation, progression, recurrence and metastasis. In human hepatocellular …

Exosomes decrease sensitivity of breast cancer cells to adriamycin by delivering microRNAs

L Mao, J Li, W Chen, Y Cai, D Yu, S Zhong, J Zhao… - Tumor Biology, 2016 - Springer
While adriamycin (adr) offers improvement in survival for breast cancer (BCa) patients,
unfortunately, drug resistance is almost inevitable. Mounting evidence suggests that exosomes …

Role of miR-155 in drug resistance of breast cancer

D Yu, M Lv, W Chen, S Zhong, X Zhang, L Chen, T Ma… - Tumor Biology, 2015 - Springer
MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expressions at
posttranscriptional level. Growing evidence points to their significant role in the acquisition of drug …

[HTML][HTML] Chromosomal level assembly and population sequencing of the Chinese tree shrew genome

Y Fan, MS Ye, JY Zhang, L Xu, DD Yu, TL Gu… - Zoological …, 2019 - ncbi.nlm.nih.gov
Chinese tree shrews (Tupaia belangeri chinensis) have become an increasingly important
experimental animal in biomedical research due to their close relationship to primates. An …