Animal genomes contain endogenous viral sequences, such as endogenous retroviruses and
retrotransposons. Recently, we and others discovered that nonretroviral viruses also have …

Hibernating mammals survive hypothermia (<10C) without injury, a remarkable feat of
cellular preservation that bears significance for potential medical applications. However, …

The ability to sense heat is crucial for survival. Increased heat tolerance may prove
beneficial by conferring the ability to inhabit otherwise prohibitive ecological niches. This …

Thirteen-lined ground squirrels and Syrian hamsters are known for their ability to withstand
cold during hibernation. We found that hibernators exhibit cold tolerance even in the active …

Long-chain PUFAs (LC-PUFAs; C20–C22; eg, DHA and arachidonic acid) are highly enriched
in vertebrate retina, where they are elongated to very-long-chain PUFAs (VLC-PUFAs; C …

Skeletal muscle atrophy is a very common clinical challenge in many disuse conditions.
Maintenance of muscle mass is crucial to combat debilitating functional consequences evoked …

Hibernating mammals possess a unique ability to reduce their body temperature to ambient
levels, which can be as low as −2.9 C, by active down-regulation of metabolism. Despite …

This presentation will survey the retinal architecture, advantages, and limitations of several
lesser-known rodent species that provide a useful diurnal complement to rats and mice. …

Hibernation in sciurid rodents is a dynamic phenotype timed by a circannual clock. When
housed in an animal facility, 13-lined ground squirrels exhibit variation in seasonal onset of …

Many inherited visual diseases arise from mutations that affect the structure and function of
photoreceptor cells. In some cases, the pathology is accompanied by a massive release of …