User profiles for Dana Pascovici
Dana PascoviciCSIRO Verified email at csiro.au Cited by 2226 |
Multiple testing corrections in quantitative proteomics: A useful but blunt tool
Multiple testing corrections are a useful tool for restricting the FDR, but can be blunt in the
context of low power, as we demonstrate by a series of simple simulations. Unfortunately, in …
context of low power, as we demonstrate by a series of simple simulations. Unfortunately, in …
[HTML][HTML] Clinically relevant post-translational modification analyses—maturing workflows and bioinformatics tools
Post-translational modifications (PTMs) can occur soon after translation or at any stage in
the lifecycle of a given protein, and they may help regulate protein folding, stability, cellular …
the lifecycle of a given protein, and they may help regulate protein folding, stability, cellular …
[HTML][HTML] Proteomic analysis indicates massive changes in metabolism prior to the inhibition of growth and photosynthesis of grapevine (Vitis viniferaL.) in response to …
Background Cabernet Sauvignon grapevines were exposed to a progressive, increasing
water defict over 16 days. Shoot elongation and photosynthesis were measured for …
water defict over 16 days. Shoot elongation and photosynthesis were measured for …
[HTML][HTML] Integrative omics identifies conserved and pathogen-specific responses of sepsis-causing bacteria
Even in the setting of optimal resuscitation in high-income countries severe sepsis and septic
shock have a mortality of 20–40%, with antibiotic resistance dramatically increasing this …
shock have a mortality of 20–40%, with antibiotic resistance dramatically increasing this …
[HTML][HTML] SWATH mass spectrometry performance using extended peptide MS/MS assay libraries
The use of data-independent acquisition methods such as SWATH for mass spectrometry
based proteomics is usually performed with peptide MS/MS assay libraries which enable …
based proteomics is usually performed with peptide MS/MS assay libraries which enable …
Shotgun proteomic analysis of long-distance drought signaling in rice roots
…, N Soltani, E Sarhadi, D Pascovici… - Journal of proteome …, 2012 - ACS Publications
Rice (Oryza sativa L. cv. IR64) was grown in split-root systems to analyze long-distance drought
signaling within root systems. This in turn underpins how root systems in heterogeneous …
signaling within root systems. This in turn underpins how root systems in heterogeneous …
Differential metabolic response of cultured rice (Oryza sativa) cells exposed to high‐ and low‐temperature stress
Global mean temperatures are expected to rise by 2–4.5C by 2100, accompanied by an
increase in frequency and amplitude of extreme temperature events. Greater climatic extremes …
increase in frequency and amplitude of extreme temperature events. Greater climatic extremes …
Differential regulation of aquaporins, small GTP ases and V‐ATP ases proteins in rice leaves subjected to drought stress and recovery
Mechanisms of drought tolerance are complex, interacting, and polygenic. This paper
describes patterns of gene expression at precise physiological stages of drought in 35‐day‐old …
describes patterns of gene expression at precise physiological stages of drought in 35‐day‐old …
Label-free quantitative shotgun proteomics using normalized spectral abundance factors
In this chapter we describe the workflow used in our laboratory for label-free quantitative
shotgun proteomics based on spectral counting. The main tools used are a series of R modules …
shotgun proteomics based on spectral counting. The main tools used are a series of R modules …
[HTML][HTML] Induction of virulence factors in Giardia duodenalis independent of host attachment
Giardia duodenalis is responsible for the majority of parasitic gastroenteritis in humans
worldwide. Host-parasite interaction models in vitro provide insights into disease and virulence …
worldwide. Host-parasite interaction models in vitro provide insights into disease and virulence …