[PDF][PDF] Gastrointestinal symptoms and fecal shedding of SARS-CoV-2 RNA suggest prolonged gastrointestinal infection
Background COVID-19 manifests with respiratory, systemic, and gastrointestinal (GI)
symptoms. SARS-CoV-2 RNA is detected in respiratory and fecal samples, and recent reports …
symptoms. SARS-CoV-2 RNA is detected in respiratory and fecal samples, and recent reports …
Human gut bacteria contain acquired interbacterial defence systems
The human gastrointestinal tract consists of a dense and diverse microbial community, the
composition of which is intimately linked to health. Extrinsic factors such as diet and host …
composition of which is intimately linked to health. Extrinsic factors such as diet and host …
Functional metagenomics-guided discovery of potent Cas9 inhibitors in the human microbiome
KJ Forsberg, IV Bhatt, DT Schmidtke, K Javanmardi… - elife, 2019 - elifesciences.org
10.7554/eLife.46540.001 CRISPR-Cas systems protect bacteria and archaea from phages
and other mobile genetic elements, which use small anti-CRISPR (Acr) proteins to overcome …
and other mobile genetic elements, which use small anti-CRISPR (Acr) proteins to overcome …
[HTML][HTML] The novel anti-CRISPR AcrIIA22 relieves DNA torsion in target plasmids and impairs SpyCas9 activity
KJ Forsberg, DT Schmidtke, R Werther, RV Uribe… - PLoS …, 2021 - journals.plos.org
To overcome CRISPR-Cas defense systems, many phages and mobile genetic elements (MGEs)
encode CRISPR-Cas inhibitors called anti-CRISPRs (Acrs). Nearly all characterized …
encode CRISPR-Cas inhibitors called anti-CRISPRs (Acrs). Nearly all characterized …
The Tomato Brown Rugose Fruit Virus Movement Protein Gene Is a Novel Microbial Source Tracking Marker
A Natarajan, BJ Fremin, DT Schmidtke… - Applied and …, 2023 - Am Soc Microbiol
Microbial source tracking (MST) identifies sources of fecal contamination in the environment
using host-associated fecal markers. While there are numerous bacterial MST markers that …
using host-associated fecal markers. While there are numerous bacterial MST markers that …
[HTML][HTML] Paths to adaptation under fluctuating nitrogen starvation: The spectrum of adaptive mutations in Saccharomyces cerevisiae is shaped by retrotransposons …
M Hays, K Schwartz, DT Schmidtke, D Aggeli… - PLoS …, 2023 - journals.plos.org
There are many mechanisms that give rise to genomic change: while point mutations are
often emphasized in genomic analyses, evolution acts upon many other types of genetic …
often emphasized in genomic analyses, evolution acts upon many other types of genetic …
Analysis and culturing of the prototypic crAssphage reveals a phage-plasmid lifestyle
DT Schmidtke, AS Hickey, I Liachko, GJ Sherlock… - bioRxiv, 2024 - biorxiv.org
The prototypic crAssphage (Carjivirus communis) is one of the most abundant, prevalent,
and persistent gut bacteriophages, yet it remains uncultured and its lifestyle uncharacterized. …
and persistent gut bacteriophages, yet it remains uncultured and its lifestyle uncharacterized. …
Acquired interbacterial defense systems protect against interspecies antagonism in the human gut microbiome
BD Ross, AJ Verster, MC Radey, DT Schmidtke… - bioRxiv, 2018 - biorxiv.org
The genomes of bacteria derived from the gut microbiota are replete with pathways that
mediate contact-dependent interbacterial antagonism. However, the role of direct interactions …
mediate contact-dependent interbacterial antagonism. However, the role of direct interactions …
[HTML][HTML] Tomato brown rugose fruit virus Mo gene is a novel microbial source tracking marker
A Natarajan, BJ Fremin, DT Schmidtke, MK Wolfe… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Microbial source tracking (MST) identifies sources of fecal contamination in the environment
using fecal host-associated markers. While there are numerous bacterial MST markers, …
using fecal host-associated markers. While there are numerous bacterial MST markers, …
Stool Screening for Sars-Cov-2 RNA for COVID-19 in Patients Undergoing Hematopoietic Cell Transplantation, Cellular Therapy, and Induction Chemotherapy
CJ Severyn, A Natarajan, DT Schmidtke… - … and Cellular Therapy, 2023 - ncbi.nlm.nih.gov
Conclusion: Recipients of HSCT and CAR T-cell therapy are at risk of breakthrough COVID-19
infections despite use of pre-exposure prophylaxis with tixagevimab-cilgavimab. However…
infections despite use of pre-exposure prophylaxis with tixagevimab-cilgavimab. However…