Stroke, in association with its complications, is one of the leading causes of mortality and
morbidity worldwide. Cerebral ischemia triggers an inflammatory response in the brain that is …

CD4 + T lymphocytes are key mediators of tissue damage after ischemic stroke. However,
their infiltration kinetics and interactions with other immune cells in the delayed phase of …

Stroke is the second leading cause of death and disability worldwide. Current treatments, such
as pharmacological thrombolysis or mechanical thrombectomy, reopen occluded arteries …

IgG4 subclass antibodies represent the rarest subclass of IgG antibodies, comprising only 3-5%
of antibodies circulating in the bloodstream. These antibodies possess unique structural …

Alzheimer’s disease and small vessel ischemic disease frequently co-exist in the aging brain.
However, pathogenic links between these 2 disorders are yet to be identified. Therefore …

Stroke-induced immunosuppression contributes to the development of stroke-associated
pneumonia (SAP). Experiments in mice demonstrated that apoptosis of IFN-γ producing cells …

Stroke is one of the leading causes of mortality and morbidity worldwide. Upon cerebral
ischemia, an inflammatory reaction takes place in the brain. Infiltration of different immune cell …

BACKGROUND: Prediction of poststroke outcome using the degree of subacute deficit or
magnetic resonance imaging is well studied in humans. While mice are the most commonly …

Recently, several genome-wide association studies identified PHACTR1 as key locus for
five diverse vascular disorders: coronary artery disease, migraine, fibromuscular dysplasia, …

Pneumonia is the most frequent severe medical complication after stroke. An overactivation
of the cholinergic signaling after stroke contributes to immunosuppression and the …