Autophagy controls mesenchymal stem cell properties and senescence during bone aging
Y Ma, M Qi, Y An, L Zhang, R Yang, DH Doro, W Liu… - Aging cell, 2018 - Wiley Online Library
Bone marrow‐derived mesenchymal stem cells ( BMMSC s) exhibit degenerative changes,
including imbalanced differentiation and reduced proliferation during aging, that contribute to …
including imbalanced differentiation and reduced proliferation during aging, that contribute to …
Wnt-modified materials mediate asymmetric stem cell division to direct human osteogenic tissue formation for bone repair
The maintenance of human skeletal stem cells (hSSCs) and their progeny in bone defects is
a major challenge. Here, we report on a transplantable bandage containing a three-…
a major challenge. Here, we report on a transplantable bandage containing a three-…
[HTML][HTML] Calvarial suture-derived stem cells and their contribution to cranial bone repair
DH Doro, AE Grigoriadis, KJ Liu - Frontiers in Physiology, 2017 - frontiersin.org
In addition to the natural turnover during life, the bones in the skeleton possess the ability to
self-repair in response to injury or disease-related bone loss. Based on studies of bone …
self-repair in response to injury or disease-related bone loss. Based on studies of bone …
[HTML][HTML] Promotion of neutralizing antibody-independent immunity to wild-type and SARS-CoV-2 variants of concern using an RBD-Nucleocapsid fusion protein
…, R Magalhães, B Cassaro, G Burle, D Doro… - Nature …, 2022 - nature.com
Both T cells and B cells have been shown to be generated after infection with SARS-CoV-2
yet protocols or experimental models to study one or the other are less common. Here, we …
yet protocols or experimental models to study one or the other are less common. Here, we …
[HTML][HTML] Improved canine and human visceral leishmaniasis immunodiagnosis using combinations of synthetic peptides in enzyme-linked immunosorbent assay
…, M Penido, MS Dos Santos, D Doro… - PLoS Neglected …, 2012 - journals.plos.org
Background Zoonotic visceral leishmaniasis (VL) is a severe infectious disease caused by
protozoan parasites of the genus Leishmania and the domestic dogs are the main urban …
protozoan parasites of the genus Leishmania and the domestic dogs are the main urban …
[HTML][HTML] Differential requirement of neutralizing antibodies and T cells on protective immunity to SARS-CoV-2 variants of concern
…, ER Oliveira, MM Figueiredo, AF Carvalho, D Doro… - npj Vaccines, 2023 - nature.com
The current COVID-19 vaccines protect against severe disease, but are not effective in
controlling replication of the Variants of Concern (VOCs). Here, we used the existing pre-clinical …
controlling replication of the Variants of Concern (VOCs). Here, we used the existing pre-clinical …
[HTML][HTML] Glycogen synthase kinase 3 controls migration of the neural crest lineage in mouse and Xenopus
…, AM Lopez Muñoz, D Doro… - Nature …, 2018 - nature.com
Neural crest migration is critical to its physiological function. Mechanisms controlling mammalian
neural crest migration are comparatively unknown, due to difficulties accessing this cell …
neural crest migration are comparatively unknown, due to difficulties accessing this cell …
[HTML][HTML] The osteogenic potential of the neural crest lineage may contribute to craniosynostosis
D Doro, A Liu, AE Grigoriadis, KJ Liu - Molecular syndromology, 2019 - karger.com
The craniofacial skeleton is formed from the neural crest and mesodermal lineages, both of
which contribute mesenchymal precursors during formation of the skull bones. The large …
which contribute mesenchymal precursors during formation of the skull bones. The large …
[HTML][HTML] Cranial suture lineage and contributions to repair of the mouse skull
D Doro, A Liu, JS Lau, AK Rajendran, C Healy… - …, 2024 - journals.biologists.com
The cranial sutures are proposed to be a stem cell niche, harbouring skeletal stem cells that
are directly involved in development, homeostasis and healing. Like the craniofacial bones, …
are directly involved in development, homeostasis and healing. Like the craniofacial bones, …
[HTML][HTML] New Vaccine Formulations Containing a Modified Version of the Amastigote 2 Antigen and the Non-Virulent Trypanosoma cruzi CL-14 Strain Are Highly Antigenic and …
APMM Almeida, LFM Machado, D Doro… - Frontiers in …, 2018 - frontiersin.org
Visceral leishmaniasis (VL) is a major public health issue reported as the second illness in
mortality among all tropical diseases. Clinical trials have shown that protection against VL is …
mortality among all tropical diseases. Clinical trials have shown that protection against VL is …