User profiles for Daniel Hitchcock

Daniel R. Hitchcock

Clemson University
Verified email at clemson.edu
Cited by 421

[PDF][PDF] Bacteroides-derived sphingolipids are critical for maintaining intestinal homeostasis and symbiosis

EM Brown, X Ke, D Hitchcock, S Jeanfavre… - Cell host & …, 2019 - cell.com
Sphingolipids are structural membrane components and important eukaryotic signaling
molecules. Sphingolipids regulate inflammation and immunity and were recently identified as the …

Ornithine aminotransferase supports polyamine synthesis in pancreatic cancer

…, A Lorzadeh, G Ye, T Zaytouni, A Adler, DS Hitchcock… - Nature, 2023 - nature.com
There is a need to develop effective therapies for pancreatic ductal adenocarcinoma (PDA),
a highly lethal malignancy with increasing incidence 1 and poor prognosis 2 . Although …

[HTML][HTML] Starved epithelial cells uptake extracellular matrix for survival

…, J Hwang, CD DuBois, JL Coloff, DS Hitchcock… - Nature …, 2017 - nature.com
Extracellular matrix adhesion is required for normal epithelial cell survival, nutrient uptake
and metabolism. This requirement can be overcome by oncogene activation. Interestingly, …

A prospective analysis of circulating plasma metabolites associated with ovarian cancer risk

…, S Jeanfavre, AA Deik, K Bullock, DS Hitchcock… - Cancer research, 2020 - AACR
Daniel S. HitchcockHitchcock, Julian Avila-Pacheco, Clary B. Clish, Shelley S. Tworoger;
A Prospective Analysis of Circulating Plasma Metabolites Associated with Ovarian Cancer Risk…

[HTML][HTML] Critical role for arginase 2 in obesity-associated pancreatic cancer

T Zaytouni, PY Tsai, DS Hitchcock, CD DuBois… - Nature …, 2017 - nature.com
Obesity is an established risk factor for pancreatic ductal adenocarcinoma (PDA). Despite
recent identification of metabolic alterations in this lethal malignancy, the metabolic …

[HTML][HTML] Water use and treatment in container-grown specialty crop production: A review

…, RT Fernandez, PR Fisher, DR Hitchcock… - Water, Air, & Soil …, 2017 - Springer
While governments and individuals strive to maintain the availability of high-quality water
resources, many factors can “change the landscape” of water availability and quality, including …

Dissolved organic matter and nutrient dynamics of a coastal freshwater forested wetland in Winyah Bay, South Carolina

AT Chow, J Dai, WH Conner, DR Hitchcock, JJ Wang - Biogeochemistry, 2013 - Springer
Seasonally flooded, freshwater cypress-tupelo wetlands, dominated by baldcypress (Taxodium
distictum), water tupelo (Nyssa aquatica), and swamp tupelo (Nyssa sylvatica var. biflora) …

Adaptation of pancreatic cancer cells to nutrient deprivation is reversible and requires glutamine synthetase stabilization by mTORC1

…, CA Lewis, DS Hitchcock… - Proceedings of the …, 2021 - National Acad Sciences
Pancreatic ductal adenocarcinoma (PDA) is a lethal, therapy-resistant cancer that thrives in
a highly desmoplastic, nutrient-deprived microenvironment. Several studies investigated the …

Potential Effect of Migration Strategy on Pollutant Occurrence in Eggs of Arctic Breeding Barnacle Geese (Branta leucopsis)

DJ Hitchcock, T Andersen, Ø Varpe… - … science & technology, 2019 - ACS Publications
Arctic-breeding geese acquire resources for egg production from overwintering grounds,
spring stopover sites and breeding grounds, where pollutant exposure may differ. We …

Physiological and emotional reactivity to learning and frustration

M Lewis, DFA Hitchcock, MW Sullivan - Infancy, 2004 - Wiley Online Library
This study examined the behavioral (arm, facial) and autonomic (heart rate, respiratory sinus
arrhythmia [RSA], and adrenocortical axis) reactivity of 56 4‐month‐old infants in response …