Exercise-induced muscle damage: What is it, what causes it and what are the nutritional solutions?

DJ Owens, C Twist, JN Cobley… - European journal of …, 2019 - Taylor & Francis
Exercise-induced muscle damage (EIMD) is characterized by symptoms that present both
immediately and for up to 14 days after the initial exercise bout. The main consequence of …

[HTML][HTML] Vitamin D and the athlete: current perspectives and new challenges

DJ Owens, R Allison, GL Close - Sports medicine, 2018 - Springer
The last decade has seen a dramatic increase in general interest in and research into vitamin
D, with many athletes now taking vitamin D supplements as part of their everyday dietary …

The effects of vitamin D3 supplementation on serum total 25 [OH] D concentration and physical performance: a randomised dose–response study

…, M Patterson, W Bradley, DJ Owens… - British journal of sports …, 2013 - bjsm.bmj.com
Background Vitamin D deficiency is common in the general public and athletic populations
and may impair skeletal muscle function. We therefore assessed the effects of vitamin D 3 …

[HTML][HTML] A systems-based investigation into vitamin D and skeletal muscle repair, regeneration, and hypertrophy

DJ Owens, AP Sharples, I Polydorou… - American Journal …, 2015 - journals.physiology.org
Skeletal muscle is a direct target for vitamin D. Observational studies suggest that low 25 [OH]
D correlates with functional recovery of skeletal muscle following eccentric contractions in …

Vitamin D and the athlete: emerging insights

DJ Owens, WD Fraser, GL Close - European journal of sport …, 2015 - Taylor & Francis
Interest in Vitamin D has risen considerably recently with many athletes now advised to take
daily vitamin D supplements. The reason for this interest is partly not only attributed to the …

Efficacy of High Dose Vitamin D Supplements for Elite Athletes.

DJ Owens, JCY Tang, WJ Bradley… - … and science in …, 2016 - researchonline.ljmu.ac.uk
PURPOSE: Supplementation with dietary forms of vitamin D is commonplace in clinical
medicine, elite athletic cohorts and the general population, yet the response of all major vitamin …

UBR5 is a novel E3 ubiquitin ligase involved in skeletal muscle hypertrophy and recovery from atrophy

…, DC Hughes, DC Turner, DJ Owens… - The Journal of …, 2019 - Wiley Online Library
Key points We have recently identified that a HECT domain E3 ubiquitin ligase, named UBR5,
is altered epigenetically (via DNA methylation) after human skeletal muscle hypertrophy, …

Skeletal muscle cells possess a 'memory'of acute early life TNF-α exposure: role of epigenetic adaptation

AP Sharples, I Polydorou, DC Hughes, DJ Owens… - Biogerontology, 2016 - Springer
Sufficient quantity and quality of skeletal muscle is required to maintain lifespan and
healthspan into older age. The concept of skeletal muscle programming/memory has been …

[HTML][HTML] Lamin mutations cause increased YAP nuclear entry in muscle stem cells

DJ Owens, M Fischer, S Jabre, S Moog, K Mamchaoui… - Cells, 2020 - mdpi.com
Mutations in the LMNA gene, encoding the nuclear envelope A-type lamins, are responsible
for muscular dystrophies, the most severe form being the LMNA-related congenital …

l‐glutamine Improves Skeletal Muscle Cell Differentiation and Prevents Myotube Atrophy After Cytokine (TNF‐α) Stress Via Reduced p38 MAPK Signal Transduction

M Girven, HF Dugdale, DJ Owens… - Journal of cellular …, 2016 - Wiley Online Library
Tumour Necrosis Factor‐Alpha (TNF‐α) is chronically elevated in conditions where skeletal
muscle loss occurs. As l‐glutamine can dampen the effects of inflamed environments, we …