Regulation of firing of dopaminergic neurons and control of goal-directed behaviors
There are several brain regions that have been implicated in the control of motivated
behavior and whose disruption leads to the pathophysiology observed in major psychiatric …
behavior and whose disruption leads to the pathophysiology observed in major psychiatric …
Hippocampal dysregulation of dopamine system function and the pathophysiology of schizophrenia
Substantial evidence suggests that psychosis in schizophrenia is associated with
dysregulation of subcortical dopamine system function. Here we examine evidence that this …
dysregulation of subcortical dopamine system function. Here we examine evidence that this …
Developmental pathology, dopamine, stress and schizophrenia
Psychological stress is a contributing factor for a wide variety of neuropsychiatric diseases
including substance use disorders, anxiety, depression and schizophrenia. However, it has …
including substance use disorders, anxiety, depression and schizophrenia. However, it has …
A loss of parvalbumin-containing interneurons is associated with diminished oscillatory activity in an animal model of schizophrenia
Decreased GABAergic signaling is among the more robust pathologies observed postmortem
in schizophrenia; however, the functional consequences of this deficit are still largely …
in schizophrenia; however, the functional consequences of this deficit are still largely …
Aberrant hippocampal activity underlies the dopamine dysregulation in an animal model of schizophrenia
Evidence supports a dysregulation of subcortical dopamine (DA) system function as a
common etiology of psychosis; however, the factors responsible for this aberrant DA system …
common etiology of psychosis; however, the factors responsible for this aberrant DA system …
[HTML][HTML] The hippocampus modulates dopamine neuron responsivity by regulating the intensity of phasic neuron activation
Aberrant dopamine (DA) signaling has been advanced as a contributing factor to the
pathophysiology of a number of psychiatric conditions including schizophrenia; however, the many …
pathophysiology of a number of psychiatric conditions including schizophrenia; however, the many …
[HTML][HTML] Wikipedia: a key tool for global public health promotion
…, B Thomas, W Stomp, MF Martone, DJ Lodge… - Journal of medical …, 2011 - jmir.org
The Internet has become an important health information resource for patients and the
general public. Wikipedia, a collaboratively written Web-based encyclopedia, has become the …
general public. Wikipedia, a collaboratively written Web-based encyclopedia, has become the …
Gestational methylazoxymethanol acetate administration: a developmental disruption model of schizophrenia
Animal models are critical for the study of psychiatric disorders since they allow the use of
invasive methods that cannot be used for ethical reasons in humans. Currently there are three …
invasive methods that cannot be used for ethical reasons in humans. Currently there are three …
Activation of a ventral hippocampus–medial prefrontal cortex pathway is both necessary and sufficient for an antidepressant response to ketamine
A single sub-anesthetic dose of ketamine exerts rapid and sustained antidepressant effects.
Here, we examined the role of the ventral hippocampus (vHipp)-medial prefrontal cortex (…
Here, we examined the role of the ventral hippocampus (vHipp)-medial prefrontal cortex (…
Aversive stimuli alter ventral tegmental area dopamine neuron activity via a common action in the ventral hippocampus
Stress is a physiological, adaptive response to changes in the environment, but can also
lead to pathological alterations, such as relapse in psychiatric disorders and drug abuse. …
lead to pathological alterations, such as relapse in psychiatric disorders and drug abuse. …