[HTML][HTML] Discovery of single nucleotide polymorphisms in candidate genes associated with fertility and production traits in Holstein cattle
Background Identification of single nucleotide polymorphisms (SNPs) for specific genes
involved in reproduction might improve reliability of genomic estimates for these low-heritability …
involved in reproduction might improve reliability of genomic estimates for these low-heritability …
[HTML][HTML] Cattle sex-specific recombination and genetic control from a large pedigree analysis
…, A Padhi, C Sun, DM Bickhart, JB Cole, DJ Null… - PLoS …, 2015 - journals.plos.org
Meiotic recombination is an essential biological process that generates genetic diversity
and ensures proper segregation of chromosomes during meiosis. From a large USDA dairy …
and ensures proper segregation of chromosomes during meiosis. From a large USDA dairy …
[HTML][HTML] Genome-wide association mapping for identification of quantitative trait loci for rectal temperature during heat stress in Holstein cattle
Heat stress compromises production, fertility, and health of dairy cattle. One mitigation strategy
is to select individuals that are genetically resistant to heat stress. Most of the negative …
is to select individuals that are genetically resistant to heat stress. Most of the negative …
[HTML][HTML] Identification of a nonsense mutation in APAF1 that is likely causal for a decrease in reproductive efficiency in Holstein dairy cattle
HA Adams, TS Sonstegard, PM VanRaden, DJ Null… - Journal of dairy …, 2016 - Elsevier
The HH1 haplotype on chromosome 5 is associated with a reduced conception rate and a
deficit of homozygotes at the population level in Holstein cattle. The source HH1 haplotype …
deficit of homozygotes at the population level in Holstein cattle. The source HH1 haplotype …
[HTML][HTML] Identification of a nonsense mutation in CWC15 associated with decreased reproductive efficiency in Jersey cattle
With the recent advent of genomic tools for cattle, several recessive conditions affecting fertility
have been identified and selected against, such as deficiency of uridine monophosphate …
have been identified and selected against, such as deficiency of uridine monophosphate …
[HTML][HTML] Convergent evolution of slick coat in cattle through truncation mutations in the prolactin receptor
…, J Sun, E Crespo, N Amati, JB Cole, DJ Null… - Frontiers in …, 2018 - frontiersin.org
… The distribution of phenotypes and genotypes were divergent from the null (χ 2 test p-… null
(χ 2 test p-value = 1.00 × 10 -6 , n = 70), the Carora data showed no divergence from the null …
(χ 2 test p-value = 1.00 × 10 -6 , n = 70), the Carora data showed no divergence from the null …
Diversity and population-genetic properties of copy number variations and multicopy genes in cattle
The diversity and population genetics of copy number variation (CNV) in domesticated
animals are not well understood. In this study, we analysed 75 genomes of major taurine and …
animals are not well understood. In this study, we analysed 75 genomes of major taurine and …
Single nucleotide polymorphisms in candidate genes associated with fertilizing ability of sperm and subsequent embryonic development in cattle
SD Cochran, JB Cole, DJ Null… - Biology of …, 2013 - academic.oup.com
Fertilization and development of the preimplantation embryo is under genetic control. The
present goal was to test 434 single nucleotide polymorphisms (SNPs) for association with …
present goal was to test 434 single nucleotide polymorphisms (SNPs) for association with …
[HTML][HTML] Association of single nucleotide polymorphisms in candidate genes previously related to genetic variation in fertility with phenotypic measurements of …
Many genetic markers related to health or production traits are not evaluated in populations
independent of the discovery population or related to phenotype. Here we evaluated 68 …
independent of the discovery population or related to phenotype. Here we evaluated 68 …
A single nucleotide polymorphism in COQ9 affects mitochondrial and ovarian function and fertility in Holstein cows
…, P Tribulo, LGB Siqueira, DJ Null… - Biology of …, 2017 - academic.oup.com
A single missense mutation at position 159 of coenzyme Q9 (COQ9) (G→A; rs109301586)
has been associated with genetic variation in fertility in Holstein cattle, with the A allele …
has been associated with genetic variation in fertility in Holstein cattle, with the A allele …