[HTML][HTML] Discovery of single nucleotide polymorphisms in candidate genes associated with fertility and production traits in Holstein cattle

SD Cochran, JB Cole, DJ Null, PJ Hansen - BMC genetics, 2013 - Springer
Background Identification of single nucleotide polymorphisms (SNPs) for specific genes
involved in reproduction might improve reliability of genomic estimates for these low-heritability …

[HTML][HTML] Cattle sex-specific recombination and genetic control from a large pedigree analysis

…, A Padhi, C Sun, DM Bickhart, JB Cole, DJ Null… - PLoS …, 2015 - journals.plos.org
Meiotic recombination is an essential biological process that generates genetic diversity
and ensures proper segregation of chromosomes during meiosis. From a large USDA dairy …

[HTML][HTML] Genome-wide association mapping for identification of quantitative trait loci for rectal temperature during heat stress in Holstein cattle

S Dikmen, JB Cole, DJ Null, PJ Hansen - PloS one, 2013 - journals.plos.org
Heat stress compromises production, fertility, and health of dairy cattle. One mitigation strategy
is to select individuals that are genetically resistant to heat stress. Most of the negative …

[HTML][HTML] Identification of a nonsense mutation in APAF1 that is likely causal for a decrease in reproductive efficiency in Holstein dairy cattle

HA Adams, TS Sonstegard, PM VanRaden, DJ Null… - Journal of dairy …, 2016 - Elsevier
The HH1 haplotype on chromosome 5 is associated with a reduced conception rate and a
deficit of homozygotes at the population level in Holstein cattle. The source HH1 haplotype …

[HTML][HTML] Identification of a nonsense mutation in CWC15 associated with decreased reproductive efficiency in Jersey cattle

…, JB Cole, PM VanRaden, CP Van Tassell, DJ Null… - PloS one, 2013 - journals.plos.org
With the recent advent of genomic tools for cattle, several recessive conditions affecting fertility
have been identified and selected against, such as deficiency of uridine monophosphate …

[HTML][HTML] Convergent evolution of slick coat in cattle through truncation mutations in the prolactin receptor

…, J Sun, E Crespo, N Amati, JB Cole, DJ Null… - Frontiers in …, 2018 - frontiersin.org
… The distribution of phenotypes and genotypes were divergent from the null (χ 2 test p-… null
(χ 2 test p-value = 1.00 × 10 -6 , n = 70), the Carora data showed no divergence from the null

Diversity and population-genetic properties of copy number variations and multicopy genes in cattle

…, JB Cole, DJ Null, SG Schroeder, J Song… - DNA …, 2016 - academic.oup.com
The diversity and population genetics of copy number variation (CNV) in domesticated
animals are not well understood. In this study, we analysed 75 genomes of major taurine and …

Single nucleotide polymorphisms in candidate genes associated with fertilizing ability of sperm and subsequent embryonic development in cattle

SD Cochran, JB Cole, DJ Null… - Biology of …, 2013 - academic.oup.com
Fertilization and development of the preimplantation embryo is under genetic control. The
present goal was to test 434 single nucleotide polymorphisms (SNPs) for association with …

[HTML][HTML] Association of single nucleotide polymorphisms in candidate genes previously related to genetic variation in fertility with phenotypic measurements of …

MS Ortega, AC Denicol, JB Cole, DJ Null, JF Taylor… - Journal of dairy …, 2017 - Elsevier
Many genetic markers related to health or production traits are not evaluated in populations
independent of the discovery population or related to phenotype. Here we evaluated 68 …

A single nucleotide polymorphism in COQ9 affects mitochondrial and ovarian function and fertility in Holstein cows

…, P Tribulo, LGB Siqueira, DJ Null… - Biology of …, 2017 - academic.oup.com
A single missense mutation at position 159 of coenzyme Q9 (COQ9) (G→A; rs109301586)
has been associated with genetic variation in fertility in Holstein cattle, with the A allele …