The advent of genome-wide dense variation data provides an opportunity to investigate
ancestry in unprecedented detail, but presents new statistical challenges. We propose a novel …

High-coverage whole-genome sequence studies have so far focused on a limited number 1
of geographically restricted populations 2 , 3 , 4 , 5 , or been targeted at specific diseases, …

Powerful approaches to inferring recent or current population structure based on nearest
neighbor haplotype “coancestry” have so far been inaccessible to users without high quality …

Replicable genetic association signals have consistently been found through genome-wide
association studies in recent years. The recent dramatic expansion of study sizes improves …

Cryptococcus neoformans var. grubii is the causative agent of cryptococcal meningitis, a
significant source of mortality in immunocompromised individuals, typically human …

A large number of algorithms have been developed to classify individuals into discrete
populations using genetic data. Recent results show that the information used by both model-…

Several recent studies detected fine-scale genetic structure in human populations. Hence,
groups conventionally treated as single populations harbour significant variation in terms of …

The past years have seen the rise of genomic biobanks and mega-scale meta-analysis of
genomic data, which promises to reveal the genetic underpinnings of health and disease. …

Most complex traits evolved in the ancestors of all modern humans and have been under
negative or balancing selection to maintain the distribution of phenotypes observed today. Yet …

The process of “evolutionary diffusion,” ie, reproduction with local mutation but without
selection in a biological population, resembles standard diffusion in many ways. However, …