Tests of the gravitational inverse-square law below the dark-energy length scale
DJ Kapner, TS Cook, EG Adelberger, JH Gundlach… - Physical review …, 2007 - APS
We conducted three torsion-balance experiments to test the gravitational inverse-square
law at separations between 9.53 mm and 55 μ m, probing distances less than the dark-energy …
law at separations between 9.53 mm and 55 μ m, probing distances less than the dark-energy …
Functional connectomics spanning multiple areas of mouse visual cortex
To understand the brain we must relate neurons’ functional responses to the circuit architecture
that shapes them. Here, we present a large functional connectomics dataset with dense …
that shapes them. Here, we present a large functional connectomics dataset with dense …
[HTML][HTML] A petascale automated imaging pipeline for mapping neuronal circuits with high-throughput transmission electron microscopy
Electron microscopy (EM) is widely used for studying cellular structure and network
connectivity in the brain. We have built a parallel imaging pipeline using transmission electron …
connectivity in the brain. We have built a parallel imaging pipeline using transmission electron …
[HTML][HTML] Cell-type-specific inhibitory circuitry from a connectomic census of mouse visual cortex
Mammalian cortex features a large diversity of neuronal cell types, each with characteristic
anatomical, molecular and functional properties. Synaptic connectivity rules powerfully shape …
anatomical, molecular and functional properties. Synaptic connectivity rules powerfully shape …
Petascale neural circuit reconstruction: automated methods
…, L Elabbady, PG Fahey, E Froudarakis, D Kapner… - bioRxiv, 2021 - biorxiv.org
3D electron microscopy (EM) has been successful at mapping invertebrate nervous systems,
but the approach has been limited to small chunks of mammalian brains. To scale up to …
but the approach has been limited to small chunks of mammalian brains. To scale up to …
[HTML][HTML] CAVE: Connectome annotation versioning engine
Advances in Electron Microscopy, image segmentation and computational infrastructure
have given rise to large-scale and richly annotated connectomic datasets which are …
have given rise to large-scale and richly annotated connectomic datasets which are …
[HTML][HTML] Functional connectomics reveals general wiring rule in mouse visual cortex
…, L Elabbady, A Halageri, Z Jia, C Jordan, D Kapner… - bioRxiv, 2023 - ncbi.nlm.nih.gov
To understand how the brain computes, it is important to unravel the relationship between
circuit connectivity and function. Previous research has shown that excitatory neurons in layer …
circuit connectivity and function. Previous research has shown that excitatory neurons in layer …
Stimulus novelty uncovers coding diversity in visual cortical circuits
…, L Casal, F D'Orazi, S Daniel, SEJ de Vries, D Kapner… - bioRxiv, 2023 - biorxiv.org
The detection of novel stimuli is critical to learn and survive in a dynamic environment. Though
novel stimuli powerfully affect brain activity, their impact on specific cell types and circuits …
novel stimuli powerfully affect brain activity, their impact on specific cell types and circuits …
A scalable and modular automated pipeline for stitching of large electron microscopy datasets
G Mahalingam, R Torres, D Kapner, ET Trautman… - Elife, 2022 - elifesciences.org
Serial-section electron microscopy (ssEM) is the method of choice for studying macroscopic
biological samples at extremely high resolution in three dimensions. In the nervous system, …
biological samples at extremely high resolution in three dimensions. In the nervous system, …
Quantitative census of local somatic features in mouse visual cortex
Mammalian neocortex contains a highly diverse set of cell types. These types have been
mapped systematically using a variety of molecular, electrophysiological and morphological …
mapped systematically using a variety of molecular, electrophysiological and morphological …