User profiles for Daniel M. Czajkowsky

Daniel M. Czajkowsky

Verified email at sjtu.edu.cn
Cited by 5554

Fc‐fusion proteins: new developments and future perspectives

DM Czajkowsky, J Hu, Z Shao… - EMBO molecular medicine, 2012 - embopress.org
Since the first description in 1989 of CD4‐Fc‐fusion antagonists that inhibit human immune
deficiency virus entry into T cells, Fc‐fusion proteins have been intensely investigated for …

Biological atomic force microscopy: what is achieved and what is needed

Z Shao, J Mou, DM Czajkowsky, J Yang… - Advances in …, 1996 - Taylor & Francis
Biological atomic force microscopy (AFM) has become a rapidly developing interdisciplinary
field of research in recent years. Not only has the technique, including instrumentation and …

Vertical collapse of a cytolysin prepore moves its transmembrane β‐hairpins to the membrane

DM Czajkowsky, EM Hotze, Z Shao, RK Tweten - The EMBO journal, 2004 - embopress.org
Perfringolysin O (PFO) is a prototype of the large family of pore‐forming cholesterol‐dependent
cytolysins (CDCs). A central enigma of the cytolytic mechanism of the CDCs is that their …

The human IgM pentamer is a mushroom-shaped molecule with a flexural bias

DM Czajkowsky, Z Shao - Proceedings of the National …, 2009 - National Acad Sciences
The textbook planar model of pentameric IgM, a potent activator of complement C1q, is based
upon the crystallographic structure of IgG. Although widely accepted, key predictions of …

The vacuolating toxin from Helicobacter pylori forms hexameric pores in lipid bilayers at low pH

DM Czajkowsky, H Iwamoto… - Proceedings of the …, 1999 - National Acad Sciences
Pathogenic strains of Helicobacter pylori secrete a cytotoxin, VacA, that in the presence of
weak bases, causes osmotic swelling of acidic intracellular compartments enriched in markers …

Measurement of the electron-phonon coupling factor dependence on film thickness and grain size in Au, Cr, and Al

JL Hostetler, AN Smith, DM Czajkowsky, PM Norris - Applied optics, 1999 - opg.optica.org
Femtosecond thermoreflectance data for thin films and bulk quantities of Au, Cr, and Al are
compared with the parabolic two-step thermal diffusion model for the purpose of determining …

[HTML][HTML] Self-assembling subnanometer pores with unusual mass-transport properties

…, Y Gao, H Li, Y Liu, F Liu, DM Czajkowsky… - Nature …, 2012 - nature.com
A long-standing aim in molecular self-assembly is the development of synthetic nanopores
capable of mimicking the mass-transport characteristics of biological channels and pores. …

High-resolution atomic-force microscopy of DNA: the pitch of the double helix

J Mou, DM Czajkowsky, Y Zhang, Z Shao - FEBS letters, 1995 - Elsevier
Using a cationic lipid bilayer, we show that DNA can be reliably adsorbed to the bilayer surface
for atomic force microscopy (AFM) in aqueous buffers at high resolution. The measured …

SARS-CoV-2 infection and oxidative stress: Pathophysiological insight into thrombosis and therapeutic opportunities

MS Alam, DM Czajkowsky - Cytokine & Growth Factor Reviews, 2022 - Elsevier
The current coronavirus disease 2019 (COVID-19) pandemic has presented unprecedented
challenges to global health. Although the majority of COVID-19 patients exhibit mild-to-no …

[HTML][HTML] Sub-kb Hi-C in D. melanogaster reveals conserved characteristics of TADs between insect and mammalian cells

Q Wang, Q Sun, DM Czajkowsky, Z Shao - Nature communications, 2018 - nature.com
Topologically associating domains (TADs) are fundamental elements of the eukaryotic
genomic structure. However, recent studies suggest that the insulating complexes, CTCF/cohesin, …