Mitochondria are widely recognized as a source of reactive oxygen species (ROS) in animal
cells, where it is assumed that over-production of ROS leads to an overwhelmed antioxidant …

<p>Inflammation and infection of bovine mammary glands, commonly known as mastitis,
imposes significant losses each year in the dairy industry worldwide. While several different …

Diabetes mellitus is a major risk factor for chronic periodontitis. We investigated the effects
of type 2 diabetes on the subgingival plaque bacterial composition by applying culture-…

Bacterial community composition in blood-sucking arthropods can shift dramatically across
time and space. We used 16S rRNA gene amplification and pyrosequencing to investigate …

The amygdala processes positive and negative valence and contributes to addiction, but the
cell-type-specific gene regulatory programs involved are unknown. We generated an atlas …

The deleterious reactive carbonyls released upon oxidation of polyunsaturated fatty acids in
biological membranes are believed to foster cellular aging. Comparative studies in …

Heterothermic mammals increase the proportion of polyunsaturated fatty acids (PUFA) in their
body fats prior to entering torpor. Because PUFA have low melting points, it is thought that …

Naked mole‐rats (NMRs) are mouse‐sized mammals that exhibit an exceptionally long lifespan
(>30 vs. <4 years for mice), and resist aging‐related pathologies such as cardiovascular …

Many endotherms employ torpor during periods of resource scarcity, but this state of
substantially reduced body temperature and metabolism appears to impose significant …

Heterogeneous Stock (HS) rats are a genetically diverse outbred rat population that is widely
used for studying genetics of behavioral and physiological traits. Mapping Quantitative Trait …