User profiles for Daniel P. Nickerson
 | Daniel NickersonAssociate Professor of Biology, California State University-San Bernardino Verified email at csusb.edu Cited by 1308 |
Vps-C complexes: gatekeepers of endolysosomal traffic
Genetic studies in yeast, plants, insects, and mammals have identified four universally
conserved proteins, together called Vps Class C, that are essential for late endosome and …
conserved proteins, together called Vps Class C, that are essential for late endosome and …
Did2 coordinates Vps4-mediated dissociation of ESCRT-III from endosomes
The sorting of transmembrane cargo proteins into the lumenal vesicles of multivesicular
bodies (MVBs) depends on the recruitment of endosomal sorting complexes required for …
bodies (MVBs) depends on the recruitment of endosomal sorting complexes required for …
Subunit organization and Rab interactions of Vps-C protein complexes that control endolysosomal membrane traffic
…, CL Brett, CG Angers, DP Nickerson… - Molecular biology of …, 2011 - Am Soc Cell Biol
Traffic through late endolysosomal compartments is regulated by sequential signaling of small
G proteins of the Rab5 and Rab7 families. The Saccharomyces cerevisiae Vps-C protein …
G proteins of the Rab5 and Rab7 families. The Saccharomyces cerevisiae Vps-C protein …
Regulators of Vps4 ATPase activity at endosomes differentially influence the size and rate of formation of intralumenal vesicles
DP Nickerson, M West, R Henry… - Molecular biology of the …, 2010 - Am Soc Cell Biol
Recruitment of endosomal sorting complexes required for transport (ESCRTs) to the
cytosolic face of endosomes regulates selective inclusion of transmembrane proteins into the …
cytosolic face of endosomes regulates selective inclusion of transmembrane proteins into the …
SM proteins Sly1 and Vps33 co-assemble with Sec17 and SNARE complexes to oppose SNARE disassembly by Sec18
BT Lobingier, DP Nickerson, SY Lo, AJ Merz - Elife, 2014 - elifesciences.org
10.7554/eLife.02272.001 Secretory and endolysosomal fusion events are driven by SNAREs
and cofactors, including Sec17/α-SNAP, Sec18/NSF, and Sec1/Munc18 (SM) proteins. …
and cofactors, including Sec17/α-SNAP, Sec18/NSF, and Sec1/Munc18 (SM) proteins. …
A concentric circle model of multivesicular body cargo sorting
Targeting of ubiquitylated transmembrane proteins into luminal vesicles of endosomal
multivesicular bodies (MVBs) depends on their recognition by endosomal sorting complexes …
multivesicular bodies (MVBs) depends on their recognition by endosomal sorting complexes …
SNARE chaperone Sly1 directly mediates close-range vesicle tethering
…, BM Delgado, U Nattermann, DP Nickerson… - Journal of Cell …, 2024 - rupress.org
The essential Golgi protein Sly1 is a member of the Sec1/mammalian Unc-18 (SM) family of
SNARE chaperones. Sly1 was originally identified through remarkable gain-of-function …
SNARE chaperones. Sly1 was originally identified through remarkable gain-of-function …
Sec17 (α-SNAP) and an SM-tethering complex regulate the outcome of SNARE zippering in vitro and in vivo
ML Schwartz, DP Nickerson, BT Lobingier, RL Plemel… - Elife, 2017 - elifesciences.org
10.7554/eLife.27396.001 Zippering of SNARE complexes spanning docked membranes is
essential for most intracellular fusion events. Here, we explore how SNARE regulators …
essential for most intracellular fusion events. Here, we explore how SNARE regulators …
Termination of isoform‐selective Vps21/Rab5 signaling at endolysosomal organelles by Msb3/Gyp3
Traffic through endosomes and lysosomes is controlled by small G‐proteins of the Rab5 and
Rab7 families. Like humans, Saccharomyces cerevisiae has three Rab5s (Vps21, Ypt52 …
Rab7 families. Like humans, Saccharomyces cerevisiae has three Rab5s (Vps21, Ypt52 …
Class E compartments form in response to ESCRT dysfunction in yeast due to hyperactivity of the Vps21 Rab GTPase
MRG Russell, T Shideler, DP Nickerson… - Journal of cell …, 2012 - journals.biologists.com
The endosomal sorting complexes required for transport (ESCRTs) mediate the budding of
intralumenal vesicles (ILVs) at late endosomes. ESCRT dysfunction causes drastic changes …
intralumenal vesicles (ILVs) at late endosomes. ESCRT dysfunction causes drastic changes …