Imaging large fields of view while preserving high-resolution structural information remains a
challenge in low-dose cryo-electron tomography. Here we present robust tools for montage …

Caulobacter crescentus is a Gram-negative alphaproteobacterium that commonly lives in
oligotrophic fresh- and saltwater environments. C. crescentus is a host to many bacteriophages…

Imaging large fields of view while preserving high-resolution structural information remains
a challenge in low-dose cryo-electron tomography. Here, we present robust tools for …

Cell elongation and division are essential aspects of the bacterial life cycle that must be
coordinated for viability and replication. The impact of misregulation of these processes is not …

Escherichia coli O157:H7 is a human pathogen that resides asymptomatically in its bovine
host. The level of Shiga toxin (Stx) produced is variable in bovine-derived strains in contrast to …

Starvation of Bacillus subtilis initiates endosporulation involving formation of mother cell (MC)
and forespore (FS) compartments. During engulfment, the MC membrane migrates around …

Intramembrane proteases (IPs) cleave membrane-associated substrates in nearly all organisms
and regulate diverse processes. A better understanding of how these enzymes interact …

RasP is a predicted intramembrane metalloprotease of Bacillus subtilis that has been proposed
to cleave the stress response anti-sigma factors RsiW and RsiV, the cell division protein …

This project seeks to define the physiological responses of bacterial cells to antibiotic
treatments. This information will be used to improve our understanding of bacterial stress …

All cells share a common genetic code. From the nucleus of mammalian cells to the nucleoid
of the smallest bacterium, all cells use DNA to encode the traits and cellular processes that …