Evidence from mass‐spectrometry experiments and molecular dynamics simulations suggests
that it is possible to transfer proteins, or in general biomolecular aggregates, from solution …

There exists a conspicuous gap of knowledge about the organization of life at mesoscopic
levels. Ultra-fast coherent diffractive imaging with X-ray free-electron lasers can probe …

We overcome two of the most daunting challenges in single-particle diffractive imaging:
collecting many high-quality diffraction patterns on a small amount of sample and separating …

Single particle diffractive imaging data from Rice Dwarf Virus (RDV) were recorded using the
Coherent X-ray Imaging (CXI) instrument at the Linac Coherent Light Source (LCLS). RDV …

Ultrafast X-ray imaging on individual fragile specimens such as aerosols 1 , metastable
particles 2 , superfluid quantum systems 3 and live biospecimens 4 provides high-resolution …

Dissolution of many plant viruses is thought to start with swelling of the capsid caused by
calcium removal following infection, but no high-resolution structures of swollen capsids exist. …

The possibility of imaging single proteins constitutes an exciting challenge for x-ray lasers.
Despite encouraging results on large particles, imaging small particles has proven to be …

Single-particle diffraction from X-ray Free Electron Lasers offers the potential for molecular
structure determination without the need for crystallization. In an effort to further develop the …

This study explores the capabilities of the Coherent X-ray Imaging Instrument at the Linac
Coherent Light Source to image small biological samples. The weak signal from small …

Diffraction before destruction using X-ray free-electron lasers (XFELs) has the potential to
determine radiation-damage-free structures without the need for crystallization. This article …