Uncoupling protein 2 (UCP2) maps to a region on distal mouse chromosome 7 that has been
linked to the phenotypes of obesity and type II diabetes. We recently reported that UCP2 …

We report here the cloning and functional analysis of a novel homologue of the mitochondrial
carriers predominantly expressed in the central nervous system and referred to as BMCP1 (…

Left ventricular mass (LVM) is a highly heritable trait 1 and an independent risk factor for all-cause
mortality 2 . So far, genome-wide association studies have not identified the genetic …

In mammalian brown adipose tissue, thermogenesis is explained by uncoupling mitochondrial
respiration from ATP synthesis. Uncoupling protein‐1 (UCP1) is responsible for this …

Differentiated cardiomyocytes are resistant to caspase-dependent cell death; however, the
mechanisms involved are still uncertain. We previously reported that low Apaf1 expression …

Cardiac fibroblasts play an essential role in the physiology of the heart. These produce
extracellular matrix proteins and synthesize angiogenic and cardioprotective factors. Although …

Fas apoptosis inhibitory molecule (FAIM) is a protein identified as an antagonist of Fas-induced
cell death. We show that FAIM overexpression fails to rescue neurons from trophic factor …

The present study was conducted to investigate the brain distribution of the recently cloned
uncoupling protein 2 (UCP2). Northern blot analyses were first carried out to confirm the …

Background NF-E2-related factor 2 (Nrf2) is a transcription factor playing cytoprotective
effects in various pathological processes including oxidative stress and cardiac hypertrophy. …

TARDBP (TAR DNA binding protein) is one of the components of neuronal aggregates in
sporadic amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration. We have …