In mammals, megakaryocytes (MKs) in the bone marrow (BM) produce blood platelets,
required for hemostasis and thrombosis. MKs originate from hematopoietic stem cells and are …

Collagen receptors GPVI (also known as GP6) and integrin α2β1 are highly expressed on
blood platelets and megakaryocytes, their immediate precursors. After vessel injury, …

10.7554/eLife.46840.001 The immunoreceptor tyrosine-based inhibition motif (ITIM)-containing
receptor G6b-B is critical for platelet production and activation. Loss of G6b-B results in …

Platelets, anucleated megakaryocyte (MK)-derived cells, play a major role in hemostasis
and arterial thrombosis. Although protein kinase casein kinase 2 (CK2) is readily detected in …

Background Hermansky–Pudlak syndrome (HPS) is a rare autosomal recessive disease
characterized by oculocutaneous albinism and platelet dysfunction. We report on a novel HPS6 …

The two main collagen receptors on platelets, GPVI and integrin α2β1, play an important
role for the recognition of exposed collagen at sites of vessel injury, which leads to platelet …

Blood platelets play key roles in hemostasis and thrombosis and are the second most
abundant cell type in the circulation. Due to their short life span of only a few days, anuclear …

Platelets, small anucleated blood cells responsible for hemostasis, interact at sights of injury
with several exposed extracellular matrix (ECM) proteins through specific receptors. Ligand …

The biogenesis of blood platelets is a process referred to as thrombopoiesis. Platelets are
derived from large precursor cells residing in the bone marrow and are designated …

Fluorescence‐based biosensors have widely been used in the life‐sciences and biomedical
applications due to their low limit of detection and a diverse selection of fluorophores that …