[HTML][HTML] CD163+ macrophages restrain vascular calcification, promoting the development of high-risk plaque
…, K Kawai, T Konishi, R Fernandez, DT Fuller… - JCI insight, 2023 - ncbi.nlm.nih.gov
Vascular calcification (VC) is concomitant with atherosclerosis, yet it remains uncertain why
rupture-prone high-risk plaques do not typically show extensive calcification. Intraplaque …
rupture-prone high-risk plaques do not typically show extensive calcification. Intraplaque …
Impaired Reorganization of Centrosome Structure Underlies Human Infantile Dilated Cardiomyopathy
…, LR Neitzel, M Silver-Isenstadt, AG Cadar, DT Fuller… - Circulation, 2023 - Am Heart Assoc
Background: During cardiomyocyte maturation, the centrosome, which functions as a
microtubule organizing center in cardiomyocytes, undergoes dramatic structural reorganization …
microtubule organizing center in cardiomyocytes, undergoes dramatic structural reorganization …
[PDF][PDF] Single-cell analysis shows that adipose tissue of persons with both HIV and diabetes is enriched for clonal, cytotoxic, and CMV-specific CD4+ T cells
…, BO Woodward, LT Hannah, MA Pilkinton, DT Fuller… - Cell Reports …, 2021 - cell.com
Persons with HIV are at increased risk for diabetes mellitus compared with individuals
without HIV. Adipose tissue is an important regulator of glucose and lipid metabolism, and …
without HIV. Adipose tissue is an important regulator of glucose and lipid metabolism, and …
Genetic variants associated with unexplained sudden cardiac death in adult White and African American individuals
…, S Torii, R Fernandez, RE Braumann, DT Fuller… - JAMA …, 2021 - jamanetwork.com
Importance Unexplained sudden cardiac death (SCD) describes SCD with no cause
identified. Genetic testing helps to diagnose inherited cardiac diseases in unexplained SCD; …
identified. Genetic testing helps to diagnose inherited cardiac diseases in unexplained SCD; …
APOL1 Genetic Variants Are Associated With Increased Risk of Coronary Atherosclerotic Plaque Rupture in the Black Population
A Cornelissen, DT Fuller, R Fernandez… - … , and vascular biology, 2021 - Am Heart Assoc
Objective: Reported associations between kidney risk variants (G1 and G2) in APOL1 (apolipoprotein
L1), encoding APOL1, and cardiovascular disease have been conflicting. We …
L1), encoding APOL1, and cardiovascular disease have been conflicting. We …
Genetic linkage of oxidative stress with cardiometabolic traits in an intercross derived from hyperlipidemic mouse strains
DT Fuller, AT Grainger, A Manichaikul, W Shi - Atherosclerosis, 2020 - Elsevier
Background and aims Oxidative stress is associated with cardiometabolic traits in
observational studies, yet the underlying causal relationship remains unclear. Apolipoprotein E-…
observational studies, yet the underlying causal relationship remains unclear. Apolipoprotein E-…
[HTML][HTML] Co-registration of peripheral atherosclerotic plaques assessed by conventional CT angiography, microCT and histology in patients with chronic limb …
…, A Cornelissen, A Sakamoto, Y Sato, DT Fuller… - European Journal of …, 2021 - Elsevier
Objective To co-register conventional computed tomography angiography (CTA), with ex vivo
micro-computed tomography (microCT) and histology of popliteal atherosclerotic plaques. …
micro-computed tomography (microCT) and histology of popliteal atherosclerotic plaques. …
Clonal Proliferation Within Smooth Muscle Cells in Unstable Human Atherosclerotic Lesions
…, W Xu, L Guo, DT Fuller, T Tanaka… - … and Vascular Biology, 2023 - Am Heart Assoc
BACKGROUND: Studies in humans and mice using the expression of an X-linked gene or
lineage tracing, respectively, have suggested that clones of smooth muscle cells (SMCs) exist …
lineage tracing, respectively, have suggested that clones of smooth muscle cells (SMCs) exist …
Diversity of macrophage phenotypes and responses in atherosclerosis
…, S Kuntz, KH Paek, R Fernandez, D Fuller… - Cellular and Molecular …, 2020 - Springer
The presence of macrophages within the plaque is a defining hallmark of atherosclerosis.
Macrophages are exposed to various microenvironments such as oxidized lipids and …
Macrophages are exposed to various microenvironments such as oxidized lipids and …
[PDF][PDF] Single-cell analysis shows that adipose tissue of persons with both HIV and diabetes is enriched for clonal, cytotoxic, and CMV-specific CD4+ T cells
…, BO Woodward, LT Hannah, MA Pilkinton, DT Fuller… - Cell …, 2021 - drive.google.com
Persons with HIV are at increased risk for diabetes mellitus compared with individuals
without HIV. Adipose tissue is an important regulator of glucose and lipid metabolism, and …
without HIV. Adipose tissue is an important regulator of glucose and lipid metabolism, and …