Recent findings have demonstrated that mitochondria can be transferred between cells to
control metabolic homeostasis. Although the mitochondria of brown adipocytes comprise a …

Ferroptosis is an iron-dependent cell death caused by impaired glutathione metabolism, lipid
peroxidation and mitochondrial failure. Emerging evidences report a role for ferroptosis in …

Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease
in Western countries and is associated with aging and features of metabolic syndrome. …

Non-enzymatic antioxidant capacity (NEAC) represents a sensitive biomarker measuring
the in vivo antioxidant potential of vegetable foods. To evaluate the effectiveness of plant-…

In developing countries the rise of obesity and obesity-related metabolic disorders, such as
cardiovascular diseases and type 2 diabetes, reflects the changes in lifestyle habits and …

Cell senescence is critical in diverse aspects of organism life. It is involved in tissue development
and homeostasis, as well as in tumor suppression. Consequently, it is tightly integrated …

There is a growing interest in therapeutically targeting the inflammatory response that underlies
age-related chronic diseases including obesity and type 2 diabetes. Through integrative …

Neuronal nitric oxide synthase (nNOS) and peroxisome proliferator activated receptor γ co-activator
1α (PGC-1α) are two fundamental factors involved in the regulation of skeletal …

Obesity and type 2 diabetes are frequently complicated by excess fat accumulation in the liver,
which is known as nonalcoholic fatty liver disease (NAFLD). In this context, liver steatosis …

The standard cancer treatments include chemotherapy, radiotherapy, or their combination,
which are generally associated with a multitude of side effects ranging from discomfort to the …