User profiles for Daniele Y. Sunaga-Franze

Daniele Yumi Sunaga-Franze

Bioinformatics Scientist, Max Delbrück Center for Molecular Medicine
Verified email at mdc-berlin.de
Cited by 844

Single‐nucleus RNA sequencing of plant tissues using a nanowell‐based system

DY SunagaFranze, JM Muino, C Braeuning… - The Plant …, 2021 - Wiley Online Library
Single‐cell genomics provides unprecedented potential for research on plant development
and environmental responses. Here, we introduce a generic procedure for plant nucleus …

Single-nuclei RNA-sequencing of plant tissues

DY Sunaga-Franze, JM Muino, C Braeuning, X Xu… - BioRxiv, 2020 - biorxiv.org
Single-cell genomics provides unprecedented potential for research on plant development
and environmental responses. Here, we introduce a generic procedure for plant nuclei …

[PDF][PDF] The Wnt-driven Mll1 epigenome regulates salivary gland and head and neck cancer

…, K Scheckenbach, RO Vidal, DY Sunaga-Franze… - Cell Reports, 2019 - cell.com
We identified a regulatory system that acts downstream of Wnt/β-catenin signaling in
salivary gland and head and neck carcinomas. We show in a mouse tumor model of K14-Cre-…

GAS1 is required for NOTCH-dependent facilitation of SHH signaling in the ventral forebrain neuroepithelium

M Marczenke, DY Sunaga-Franze, O Popp… - …, 2021 - journals.biologists.com
Growth arrest-specific 1 (GAS1) acts as a co-receptor to patched 1, promoting sonic hedgehog
(SHH) signaling in the developing nervous system. GAS1 mutations in humans and …

Interferon regulatory factor 4 plays a pivotal role in the development of aGVHD-associated colitis

JT Frueh, J Campe, DY Sunaga-Franze… - …, 2024 - Taylor & Francis
Interferon regulatory factor 4 (IRF4) is a master transcription factor that regulates T helper
cell (Th) differentiation. It interacts with the Basic leucine zipper transcription factor, ATF-like (…

Mutant phosphodiesterase 3A protects the kidney from hypertension-induced damage

…, BJ McMurray, DY Sunaga-Franze… - Kidney …, 2023 - kidney-international.org
Hypertension causes kidney damage that can ultimately culminate in kidney failure. 1
Hypertension with brachydactyly (HTNB) is a rare autosomal dominant syndrome caused by gain-…

[HTML][HTML] Generation of hiPSC-derived skeletal muscle cells: exploiting the potential of skeletal muscle-derived hiPSCs

E Metzler, H Escobar, DY Sunaga-Franze, S Sauer… - Biomedicines, 2022 - mdpi.com
Cell therapies for muscle wasting disorders are on the verge of becoming a realistic clinical
perspective. Muscle precursor cells derived from human induced pluripotent stem cells (…

[HTML][HTML] Interferon Regulatory Factor 4 Is a Key Factor in Regulation of Thelper Cell Polarization in Graft-Versus-Host Disease

JT Frueh, B Rais, DY Sunaga-Franze, K Stein, S Sauer… - Blood, 2018 - Elsevier
Introduction: Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is an effective
therapy for severe malignant diseases. Following allo-HSCT, donor T cells are the driving …

Mutant phosphodiesterase 3A protects from hypertension-induced cardiac damage

…, BJ McMurray, DF Lato, D Yumi Sunaga-Franze… - Circulation, 2022 - Am Heart Assoc
Daniele Yumi Sunaga-Franze … BJ McMurry, DF Lato, Dr Sunaga-Franze, Drs Borodina and
Maass evaluated RNA-sequencing data. Dr Walter examined the G449S patient. Dr Walker-…

[HTML][HTML] Effects of diets high in animal or plant protein on oxidative stress in individuals with type 2 diabetes: A randomized clinical trial

…, S Hornemann, N Rudovich, J Raila, D Sunaga-Franze… - Redox Biology, 2020 - Elsevier
High-protein diet is a promising strategy for diabetes treatment supporting body weight
control, improving glycaemic status, cardiovascular risk factors and reducing liver fat. Here, we …