User profiles for Danielle A. Debruin
Danielle A DebruinVictoria University Verified email at vu.edu.au Cited by 163 |
[HTML][HTML] Diversity in clinical and biomedical research: a promise yet to be fulfilled
…, NE Barcelo, MJ White, DM de Bruin… - PLoS …, 2015 - journals.plos.org
Esteban Gonzalez Burchard and colleagues explore how making medical research more
diverse would aid not only social justice but scientific quality and clinical effectiveness, too.
diverse would aid not only social justice but scientific quality and clinical effectiveness, too.
Lipid metabolism in sarcopenia
Sarcopenia is an age-related disease associated with loss of muscle mass and strength. This
geriatric syndrome predisposes elderly individuals to a disability, falls, fractures, and death…
geriatric syndrome predisposes elderly individuals to a disability, falls, fractures, and death…
[HTML][HTML] The failed clinical story of myostatin inhibitors against Duchenne muscular dystrophy: exploring the biology behind the battle
Myostatin inhibition therapy has held much promise for the treatment of muscle wasting
disorders. This is particularly true for the fatal myopathy, Duchenne Muscular Dystrophy (DMD). …
disorders. This is particularly true for the fatal myopathy, Duchenne Muscular Dystrophy (DMD). …
The importance of mitochondrial quality control for maintaining skeletal muscle function across health span
As the principal energy-producing organelles of the cell, mitochondria support numerous
biological processes related to metabolism, growth, and regeneration in skeletal muscle. …
biological processes related to metabolism, growth, and regeneration in skeletal muscle. …
[HTML][HTML] Dimethyl fumarate modulates the dystrophic disease program following short-term treatment
New medicines are urgently required to treat the fatal neuromuscular disease Duchenne
muscular dystrophy (DMD). Dimethyl fumarate (DMF) is a potent immunomodulatory small …
muscular dystrophy (DMD). Dimethyl fumarate (DMF) is a potent immunomodulatory small …
[HTML][HTML] Assessment of the tocolytic nifedipine in preclinical primary models of preterm birth
Spontaneous preterm birth is the leading cause of perinatal morbidity and mortality.
Tocolytics are drugs used in cases of imminent preterm birth to inhibit uterine contractions. …
Tocolytics are drugs used in cases of imminent preterm birth to inhibit uterine contractions. …
[HTML][HTML] The effect of yearly-dose vitamin D supplementation on muscle function in mice
Supplementation with vitamin D helps to alleviate weakness and fatigue seen with deficiency.
However, large bolus doses appear to worsen the risk of falls. Whether this occurs as a …
However, large bolus doses appear to worsen the risk of falls. Whether this occurs as a …
Exercise may ameliorate the detrimental side effects of high vitamin D supplementation on muscle function in mice
DA Debruin, CA Timpani, H Lalunio… - Journal of Bone and …, 2020 - Wiley Online Library
Vitamin D is commonly prescribed to normalize deficiencies and to treat osteoporosis. However,
the effect vitamin D supplements have on skeletal muscle health is equivocal. Although …
the effect vitamin D supplements have on skeletal muscle health is equivocal. Although …
[HTML][HTML] Exploring new balance and gait factors that are associated with osteosarcopenia in patients with a previous fall and/or fracture history
Osteosarcopenic individuals have poor muscle function and increased bone fragility, which
results in a severe detriment to health outcomes. Hence, there is a necessity to discover …
results in a severe detriment to health outcomes. Hence, there is a necessity to discover …
[HTML][HTML] The Effect of Vitamin D Supplementation on Skeletal Muscle in the mdx Mouse Model of Duchenne Muscular Dystrophy
Vitamin D (VitD) has shown to be beneficial in reversing muscle weakness and atrophy
associated with VitD deficiency. Duchenne muscular dystrophy is characterized by worsening …
associated with VitD deficiency. Duchenne muscular dystrophy is characterized by worsening …