An equine SNP genotyping array was developed and evaluated on a panel of samples
representing 14 domestic horse breeds and 18 evolutionarily related species. More than 54,000 …

Objective —To determine the proportion of mixed-breed and purebred dogs with common
genetic disorders. Design —Case-control study. Animals —27,254 dogs with an inherited …

Chondrodystrophy in dogs is defined by dysplastic, shortened long bones and premature
degeneration and calcification of intervertebral discs. Independent genome-wide association …

Background To date, genome-scale analyses in the domestic horse have been limited by
suboptimal single nucleotide polymorphism (SNP) density and uneven genomic coverage of …

Over the last 20-80 million years the mammalian placenta has taken on a variety of morphologies
through both divergent and convergent evolution. Recently we have shown that the …

Hereditary equine regional dermal asthenia (HERDA), a degenerative skin disease that affects
the Quarter Horse breed, was localized to ECA1 by homozygosity mapping. Comparative …

Objective —To estimate allele frequencies of the hyperkalaemic periodic paralysis (HYPP),
lethal white foal syndrome (LWFS), glycogen branching enzyme deficiency (GBED), …

Background Gonadectomy is one of the most common procedures performed on dogs in the
United States. Neutering has been shown to reduce the risk for some diseases although …

All mammals progress through similar physiological stages throughout life, from early
development to puberty, aging, and death. Yet, the extent to which this conserved physiology …

Cleft lip with or without cleft palate (CL/P) is the most commonly occurring craniofacial birth
defect. We provide insight into the genetic etiology of this birth defect by performing genome-…