[HTML][HTML] HDAC11 promotes both NLRP3/caspase-1/GSDMD and caspase-3/GSDME pathways causing pyroptosis via ERG in vascular endothelial cells

…, J Yang, D Chen, B Wang, W Yang, L Chen… - Cell Death …, 2022 - nature.com
Histone deacetylase 11 (HDAC11), a sole member of the class IV HDAC subfamily, participates
in various cardiovascular diseases. Recent evidence showed that pyroptosis was a form …

Synergistically detachable microneedle dressing for programmed treatment of chronic wounds

T Ning, F Yang, D Chen, Z Jia, R Yuan… - Advanced …, 2022 - Wiley Online Library
Chronic wounds such as diabetic feet undergo a lifetime risk of developing into incurable
ulcers. Current treatments for chronic wounds remain unsatisfactory due to the lack of ideal …

Genome-wide association study of suicide death and polygenic prediction of clinical antecedents

…, AV Bakian, S Crowell, D Chen… - American journal of …, 2020 - Am Psychiatric Assoc
Objective: Death by suicide is a highly preventable yet growing worldwide health crisis. To
date, there has been a lack of adequately powered genomic studies of suicide, with no …

Real‐world survival of patients with advanced BRAF V600 mutated melanoma treated with front‐line BRAF/MEK inhibitors, anti‐PD‐1 antibodies, or nivolumab …

JC Moser, D Chen, S Hu‐Lieskovan… - Cancer …, 2019 - Wiley Online Library
Background The optimal treatment sequence for patients with advanced BRAF V600 mutant
melanoma is unknown. BRAF/MEK inhibition (BRAF/MEKi), single agent anti‐PD‐1 (aPD‐1) …

[HTML][HTML] Genome-wide significant regions in 43 Utah high-risk families implicate multiple genes involved in risk for completed suicide

…, Z Yu, N William, SC Das, SE Crowell, D Chen… - Molecular …, 2020 - nature.com
Suicide is the 10th leading cause of death in the United States. Although environment has
undeniable impact, evidence suggests that genetic factors play a significant role in completed …

Isoliquiritigenin from licorice flavonoids attenuates NLRP3-mediated pyroptosis by SIRT6 in vascular endothelial cells

…, Z Jin, J Yang, F Yao, Y Liu, Z Zheng, D Chen… - Journal of …, 2023 - Elsevier
Ethnopharmacologic relevance Licorice is a traditional Chinese medicine that has been
used for cardiovascular diseases. Recent studies found that supplementation with licorice …

Risk factors for hospital-acquired pressure injury in surgical critical care patients

J Alderden, LJ Cowan, JB Dimas, D Chen… - American Journal of …, 2020 - AACN
Danli Chen, MSTAT Danli Chen is a biostatistician II and Yue Zhang is an associate professor,
Danli Chen is a biostatistician II and Yue Zhang is an associate professor, Division of …

[HTML][HTML] A gold nanoparticle-based visual aptasensor for rapid detection of acetamiprid residues in agricultural products using a smartphone

C Xu, M Lin, C Song, D Chen, C Bian - RSC advances, 2022 - pubs.rsc.org
Based on the colorimetric analysis of gold nanoparticles and a smartphone readable strategy,
a stable, sensitive, and visual method was established for rapid detection of acetamiprid …

Sirt6 inhibits vascular endothelial cell pyroptosis by regulation of the Lin28b/let-7 pathway in atherosclerosis

F Yao, X Lv, Z Jin, D Chen, Z Zheng, J Yang… - International …, 2022 - Elsevier
Our previous study showed that Sirtuin 6 (Sirt6) plays an important role in the regulation of
vascular endothelial cell inflammation. Recently, studies have reported that the RNA binding …

Rhaponticum carthamoides improved energy metabolism and oxidative stress through the SIRT6/Nrf2 pathway to ameliorate myocardial injury

…, Y Xian, Z Jin, F Yao, YZ Liu, Y Deng, B Wang, D Chen… - Phytomedicine, 2022 - Elsevier
Background Rhaponticum carthamoides (Willd.) Iljin (Rha) is a member of the family
Compositae that is widely used in folk medicine as a dietary supplement to treat cardiovascular …