User profiles for David A. Borkholder

David A. Borkholder

Rochester Institute of Technology
Verified email at rit.edu
Cited by 3690

Development and application of cell-based biosensors

JJ Pancrazio, JP Whelan, DA Borkholder, W Ma… - Annals of biomedical …, 1999 - Springer
Biosensors incorporate a biological sensing element that converts a change in an immediate
environment to signals conducive for processing. Biosensors have been implemented for a …

[BOOK][B] Cell-based biosensors using microelectrodes

DA Borkholder - 1999 - search.proquest.com
Instruments for the study of living cells have historically been of significant importance for
such things as basic neuroscience and cell biology. More recent work has included extending …

A review of peristaltic micropumps

…, A Arevalo, A Alfadhel, DA Borkholder - Sensors and Actuators A …, 2021 - Elsevier
This report presents a review of progress on peristaltic micropumps since their emergence,
which have been widely used in many research fields from biology to aeronautics. This paper …

Microsystems technologies for drug delivery to the inner ear

EEL Pararas, DA Borkholder, JT Borenstein - Advanced drug delivery …, 2012 - Elsevier
The inner ear represents one of the most technologically challenging targets for local drug
delivery, but its clinical significance is rapidly increasing. The prevalence of sensorineural …

High-performance, low-voltage electroosmotic pumps with molecularly thin silicon nanomembranes

…, PM Fauchet, DA Borkholder… - Proceedings of the …, 2013 - National Acad Sciences
We have developed electroosmotic pumps (EOPs) fabricated from 15-nm-thick porous
nanocrystalline silicon (pnc-Si) membranes. Ultrathin pnc-Si membranes enable high …

[HTML][HTML] In-home cardiovascular monitoring system for heart failure: Comparative study

…, KQ Schwarz, DA Borkholder - JMIR mHealth and uHealth, 2019 - mhealth.jmir.org
Background: There is a pressing need to reduce the hospitalization rate of heart failure patients
to limit rising health care costs and improve outcomes. Tracking physiologic changes to …

Plasma-etched neural probes

DT Kewley, MD Hills, DA Borkholder, IE Opris… - Sensors and Actuators A …, 1997 - Elsevier
A new method is presented for microfabricating silicon-based neural probes that are
designed for neurobiology research. Such probes provide unique capabilities to record high-…

[HTML][HTML] Dependence of Skin-Electrode Contact Impedance on Material and Skin Hydration

K Goyal, DA Borkholder, SW Day - Sensors, 2022 - mdpi.com
Dry electrodes offer an accessible continuous acquisition of biopotential signals as part of
current in-home monitoring systems but often face challenges of high-contact impedance that …

A microfluidic cartridge to prepare spores for PCR analysis

…, M Okuzumi, F Pourahmadi, DA Borkholder… - Biosensors and …, 2000 - Elsevier
A prototype cartridge system is described that rapidly disrupts Bacillus spores by sonication,
adds PCR reagent to the disrupted spores, and dispenses the mixture into a PCR tube. The …

A nanoliter resolution implantable micropump for murine inner ear drug delivery

…, D Cormier, RD Frisina, DA Borkholder - Journal of controlled …, 2019 - Elsevier
Advances in protective and restorative biotherapies have created new opportunities to use
site-directed, programmable drug delivery systems to treat auditory and vestibular disorders. …