User profiles for David A. Specht
David A SpechtPostdoctoral Researcher, Cornell University Verified email at cornell.edu Cited by 31 |
Therapeutic efficacy of multiagent chemotherapy with drug delivery enhancement by blood-brain barrier modification in glioblastoma
EA Neuwelt, J Howieson, EP Frenkel, DH Specht… - …, 1986 - journals.lww.com
: Reversible osmotic blood-brain barrier (BBB) modification was used in 38 patients with
glioblastoma to enhance the delivery of chemotherapeutic agents. The patients ranged in age …
glioblastoma to enhance the delivery of chemotherapeutic agents. The patients ranged in age …
On the evaluation of causal models
DA Specht - Social Science Research, 1975 - Elsevier
Procedures for the evaluation of linear recursive simultaneous equation models as a whole
are considered. Likelihood-ratio tests for the evaluation and comparison of the adequacy of …
are considered. Likelihood-ratio tests for the evaluation and comparison of the adequacy of …
Efficient natural plasmid transformation of Vibrio natriegens enables zero-capital molecular biology
DA Specht, TJ Sheppard, F Kennedy, S Li… - PNAS …, 2024 - academic.oup.com
The fast-growing microbe Vibrio natriegens is capable of natural transformation where it
draws DNA in from media via an active process under physiological conditions. Using an …
draws DNA in from media via an active process under physiological conditions. Using an …
Comparison of aqueous and solid‐phase uptake for hexachlorobenzene in the tellinid clam Macoma nasuta (conrad): A mass balance approach
BL Boese, H Lee Ii, DT Specht… - … and Chemistry: An …, 1990 - Wiley Online Library
The uptake of sediment‐associated hexachlorobenzene (HCB) by the deposit‐feeding clam
Macoma nasuta (Conrad) was determined using a clam ventilation chamber. Clams were …
Macoma nasuta (Conrad) was determined using a clam ventilation chamber. Clams were …
Increased delivery of tumor-specific monoclonal antibodies to brain after osmotic blood-brain barrier modification in patients with melanoma metastatic to the central …
EA Neuwelt, DH Specht, PA Barnett, SA Dahlborg… - …, 1987 - journals.lww.com
: We evaluated the delivery of melanoma-specific radiolabeled monoclonal antibody (MAb)
Fab fragments in a pilot study of three patients with melanoma metastatic to the central …
Fab fragments in a pilot study of three patients with melanoma metastatic to the central …
Avoidance response of the estuarine amphipod Eohaustorius estuarius to polycyclic aromatic hydrocarbon‐contaminated, field‐collected sediments
…, RC Swartz, BL Boese, DT Specht - … and Chemistry: An …, 1999 - Wiley Online Library
Amphipods (Eohaustorius estuarius) were placed in two‐chamber containers with different
combinations of three contaminated sediments and a control sediment, and their distribution …
combinations of three contaminated sediments and a control sediment, and their distribution …
Massively parallel CRISPRi assays reveal concealed thermodynamic determinants of dCas12a binding
The versatility of CRISPR-Cas endonucleases as a tool for biomedical research has led to
diverse applications in gene editing, programmable transcriptional control, and nucleic acid …
diverse applications in gene editing, programmable transcriptional control, and nucleic acid …
Predicting bioaccumulation potential: a test of a fugacity-based model
SP Ferraro, H Lee, RJ Ozretich, DT Specht - Archives of environmental …, 1990 - Springer
Clams (Macoma nasuta) from an unpolluted site in Yaquina Bay, Oregon were exposed in
the laboratory for 28 days to 6 field-contaminated sediments (treatments) which varied widely …
the laboratory for 28 days to 6 field-contaminated sediments (treatments) which varied widely …
Multiple Rounds of In Vivo Random Mutagenesis and Selection in Vibrio natriegens Result in Substantial Increases in REE Binding Capacity
S Medin, A Dressel, DA Specht, TJ Sheppard… - ACS Synthetic …, 2023 - ACS Publications
Rare earth elements (REE) are essential ingredients in many modern technologies, yet their
purification remains either environmentally harmful or economically unviable. Adsorption, or …
purification remains either environmentally harmful or economically unviable. Adsorption, or …
Upper limit efficiency estimates for electromicrobial production of drop-in jet fuels
Microbes which participate in extracellular electron uptake (EEU) or H 2 oxidation have the
ability to manufacture organic compounds using electricity as the primary source of metabolic …
ability to manufacture organic compounds using electricity as the primary source of metabolic …