User profiles for David B. Brückner
David B. BrücknerEMBO & NOMIS Postdoctoral Fellow, IST Austria Verified email at ist.ac.at Cited by 540 |
Stochastic motion and transcriptional dynamics of pairs of distal DNA loci on a compacted chromosome
Chromosomes in the eukaryotic nucleus are highly compacted. However, for many functional
processes, including transcription initiation, the pairwise motion of distal chromosomal …
processes, including transcription initiation, the pairwise motion of distal chromosomal …
[HTML][HTML] Curvature induces active velocity waves in rotating spherical tissues
The multicellular organization of diverse systems, including embryos, intestines, and tumors
relies on coordinated cell migration in curved environments. In these settings, cells establish …
relies on coordinated cell migration in curved environments. In these settings, cells establish …
Stochastic nonlinear dynamics of confined cell migration in two-state systems
DB Brückner, A Fink, C Schreiber, PJF Röttgermann… - Nature Physics, 2019 - nature.com
Migrating cells in physiological processes, including development, homeostasis and cancer,
encounter structured environments and are forced to overcome physical obstacles. Yet, the …
encounter structured environments and are forced to overcome physical obstacles. Yet, the …
Learning the dynamics of cell–cell interactions in confined cell migration
DB Brückner, N Arlt, A Fink… - Proceedings of the …, 2021 - National Acad Sciences
The migratory dynamics of cells in physiological processes, ranging from wound healing to
cancer metastasis, rely on contact-mediated cell–cell interactions. These interactions play a …
cancer metastasis, rely on contact-mediated cell–cell interactions. These interactions play a …
From collections of independent, mindless robots to flexible, mobile, and directional superstructures
…, K Xie, S Cassagnere, B Tregon, DB Brückner… - Science Robotics, 2021 - science.org
A swarm of simple active particles confined in a flexible scaffold is a promising system to
make mobile and deformable superstructures. These soft structures can perform tasks that are …
make mobile and deformable superstructures. These soft structures can perform tasks that are …
Inferring the dynamics of underdamped stochastic systems
Many complex systems, ranging from migrating cells to animal groups, exhibit stochastic
dynamics described by the underdamped Langevin equation. Inferring such an equation of …
dynamics described by the underdamped Langevin equation. Inferring such an equation of …
[HTML][HTML] 3D printed protein-based robotic structures actuated by molecular motor assemblies
Upscaling motor protein activity to perform work in man-made devices has long been an
ambitious goal in bionanotechnology. The use of hierarchical motor assemblies, as realized in …
ambitious goal in bionanotechnology. The use of hierarchical motor assemblies, as realized in …
[HTML][HTML] Guiding 3D cell migration in deformed synthetic hydrogel microstructures
The ability of cells to navigate through the extracellular matrix, a network of biopolymers, is
controlled by an interplay of cellular activity and mechanical network properties. Synthetic …
controlled by an interplay of cellular activity and mechanical network properties. Synthetic …
[PDF][PDF] Area and geometry dependence of cell migration in asymmetric two-state micropatterns
A Fink, DB Brückner, C Schreiber, PJF Röttgermann… - Biophysical journal, 2020 - cell.com
Microstructured surfaces provide a unique framework to probe cell migration and cytoskeletal
dynamics in a standardized manner. Here, we report on the steady-state occupancy …
dynamics in a standardized manner. Here, we report on the steady-state occupancy …
Geometry adaptation of protrusion and polarity dynamics in confined cell migration
DB Brückner, M Schmitt, A Fink, G Ladurner… - Physical Review X, 2022 - APS
Cell migration in confining physiological environments relies on the concerted dynamics of
several cellular components, including protrusions, adhesions with the environment, and the …
several cellular components, including protrusions, adhesions with the environment, and the …