User profiles for David B. Brückner

David B. Brückner

EMBO & NOMIS Postdoctoral Fellow, IST Austria
Verified email at ist.ac.at
Cited by 540

Stochastic motion and transcriptional dynamics of pairs of distal DNA loci on a compacted chromosome

DB Brückner, H Chen, L Barinov, B Zoller, T Gregor - Science, 2023 - science.org
Chromosomes in the eukaryotic nucleus are highly compacted. However, for many functional
processes, including transcription initiation, the pairwise motion of distal chromosomal …

[HTML][HTML] Curvature induces active velocity waves in rotating spherical tissues

T Brandstätter, DB Brückner, YL Han, R Alert… - Nature …, 2023 - nature.com
The multicellular organization of diverse systems, including embryos, intestines, and tumors
relies on coordinated cell migration in curved environments. In these settings, cells establish …

Stochastic nonlinear dynamics of confined cell migration in two-state systems

DB Brückner, A Fink, C Schreiber, PJF Röttgermann… - Nature Physics, 2019 - nature.com
Migrating cells in physiological processes, including development, homeostasis and cancer,
encounter structured environments and are forced to overcome physical obstacles. Yet, the …

Learning the dynamics of cell–cell interactions in confined cell migration

DB Brückner, N Arlt, A Fink… - Proceedings of the …, 2021 - National Acad Sciences
The migratory dynamics of cells in physiological processes, ranging from wound healing to
cancer metastasis, rely on contact-mediated cell–cell interactions. These interactions play a …

From collections of independent, mindless robots to flexible, mobile, and directional superstructures

…, K Xie, S Cassagnere, B Tregon, DB Brückner… - Science Robotics, 2021 - science.org
A swarm of simple active particles confined in a flexible scaffold is a promising system to
make mobile and deformable superstructures. These soft structures can perform tasks that are …

Inferring the dynamics of underdamped stochastic systems

DB Brückner, P Ronceray, CP Broedersz - Physical review letters, 2020 - APS
Many complex systems, ranging from migrating cells to animal groups, exhibit stochastic
dynamics described by the underdamped Langevin equation. Inferring such an equation of …

[HTML][HTML] 3D printed protein-based robotic structures actuated by molecular motor assemblies

…, SK Vogel, HG Franquelim, DB Brückner… - Nature Materials, 2022 - nature.com
Upscaling motor protein activity to perform work in man-made devices has long been an
ambitious goal in bionanotechnology. The use of hierarchical motor assemblies, as realized in …

[HTML][HTML] Guiding 3D cell migration in deformed synthetic hydrogel microstructures

M Dietrich, H Le Roy, DB Brückner, H Engelke, R Zantl… - Soft Matter, 2018 - pubs.rsc.org
The ability of cells to navigate through the extracellular matrix, a network of biopolymers, is
controlled by an interplay of cellular activity and mechanical network properties. Synthetic …

[PDF][PDF] Area and geometry dependence of cell migration in asymmetric two-state micropatterns

A Fink, DB Brückner, C Schreiber, PJF Röttgermann… - Biophysical journal, 2020 - cell.com
Microstructured surfaces provide a unique framework to probe cell migration and cytoskeletal
dynamics in a standardized manner. Here, we report on the steady-state occupancy …

Geometry adaptation of protrusion and polarity dynamics in confined cell migration

DB Brückner, M Schmitt, A Fink, G Ladurner… - Physical Review X, 2022 - APS
Cell migration in confining physiological environments relies on the concerted dynamics of
several cellular components, including protrusions, adhesions with the environment, and the …