Polyoma small and middle T antigens and SV40 small t antigen form stable complexes with protein phosphatase 2A

DC Pallas, LK Shahrik, BL Martin, S Jaspers, TB Miller… - Cell, 1990 - cell.com
We have purified the 36 and 63 kd cellular proteins known to associate with polyomavirus
middle and small tumor (T) antigens and SV40 small t antigen. Microsequenclng of the 36 kd …

Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity

DR Kaplan, M Whitman, B Schaffhausen, DC Pallas… - Cell, 1987 - cell.com
The phosphorylatlon of proteins on tyrosine in vivo and in vitro was examined in ST3 cells
stimulated by platelet-derived growth factor (PDGP) and transformed by polyoma middle T …

Identification of cellular proteins that can interact specifically with the T/ElA-binding region of the retinoblastoma gene product

WG Kaelin Jr, DC Pallas, JA DeCaprio, FJ Kaye… - Cell, 1991 - cell.com
The SV40 T antigen (T)/adenovirus EIA-binding domain of the retinoblaetoma gene product
(pRB) has been fused to S. japonlcum glutathione S-transferase, and the chimera, bound to …

[PDF][PDF] Identification of specific PP2A complexes involved in human cell transformation

…, R Possemato, KT Campbell, CA Plattner, DC Pallas… - Cancer cell, 2004 - cell.com
The SV40 small t antigen (ST) interacts with the serine-threonine protein phosphatase 2A (PP2A).
To investigate the role of this interaction in transformation, we suppressed the …

Striatin assembles a membrane signaling complex necessary for rapid, nongenomic activation of endothelial NO synthase by estrogen receptor α

Q Lu, DC Pallas, HK Surks, WE Baur… - Proceedings of the …, 2004 - National Acad Sciences
Steroid hormone receptors (SHRs) are ligand-activated transcription factors that regulate
gene expression. SHRs also mediate rapid, nongenomic cellular activation by steroids. In …

Analysis of the adenovirus E1B-55K-anchored proteome reveals its link to ubiquitination machinery

…, A Shevchenko, A Shevchenko, DC Pallas… - Journal of …, 2002 - Am Soc Microbiol
During the early phase of infection, the E1B-55K protein of adenovirus type 5 (Ad5) counters
the E1A-induced stabilization of p53, whereas in the late phase, E1B-55K modulates the …

FMRP phosphorylation reveals an immediate-early signaling pathway triggered by group I mGluR and mediated by PP2A

…, V Nalavadi, M Nakamoto, DC Pallas… - Journal of …, 2007 - Soc Neuroscience
Fragile X syndrome is a common form of inherited mental retardation and is caused by loss
of fragile X mental retardation protein (FMRP), a selective RNA-binding protein that …

[HTML][HTML] A protein phosphatase methylesterase (PME-1) is one of several novel proteins stably associating with two inactive mutants of protein phosphatase 2A

…, EK Mak, XX Yu, WS Lane, DC Pallas - Journal of Biological …, 1999 - ASBMB
Carboxymethylation of proteins is a highly conserved means of regulation in eukaryotic cells.
The protein phosphatase 2A (PP2A) catalytic (C) subunit is reversibly methylated at its …

STRIPAK complexes: structure, biological function, and involvement in human diseases

J Hwang, DC Pallas - The international journal of biochemistry & cell …, 2014 - Elsevier
The mammalian striatin family consists of three proteins, striatin, S/G 2 nuclear autoantigen,
and zinedin. Striatin family members have no intrinsic catalytic activity, but rather function as …

[HTML][HTML] WD40 repeat proteins striatin and S/G2 nuclear autoantigen are members of a novel family of calmodulin-binding proteins that associate with protein …

…, D Ashby, F Hubalek, WS Lane, DC Pallas - Journal of Biological …, 2000 - ASBMB
Protein phosphatase 2A (PP2A) is a multifunctional serine/threonine phosphatase that is
critical to many cellular processes including development, neuronal signaling, cell cycle …