INTRODUCTION Control of mosquito vectors has historically proven to be an effective
means of eliminating malaria. Human malaria is transmitted only by mosquitoes in the genus …

In insects, odor cues are discriminated through a divergent family of odorant receptors (ORs).
A functional OR complex consists of both a conventional odorant-binding OR and a …

Background Chemosensory signal transduction guides the behavior of many insects, including
Anopheles gambiae, the major vector for human malaria in sub-Saharan Africa. To better …

The domestication of animals, plants, and microbes fundamentally transformed the lifestyle
and demography of the human species [1]. Although the genetic and functional …

Olfactory-driven behaviors are central to the lifecycle of the malaria vector mosquito Anopheles
gambiae and are initiated by peripheral signaling in the antenna and other olfactory …

Shortly after the agricultural revolution, the domestication of bacteria, yeasts, and molds,
played an essential role in enhancing the stability, quality, flavor, and texture of food products. …

Background Two sibling members of the Anopheles gambiae species complex display
notable differences in female blood meal preferences. An. gambiae ss has a well-documented …

Eurasians have ~2% Neanderthal ancestry, but we lack a comprehensive understanding of
the genome-wide influence of Neanderthal introgression on modern human diseases and …

Background Insect odorant receptors (ORs) function as odorant-gated ion channels consisting
of a conventional, odorant-binding OR and the Orco coreceptor. While Orco can function …

Polar bear (Ursus maritimus) and brown bear (Ursus arctos) are recently diverged species
that inhabit vastly differing habitats. Thus, analysis of the polar bear and brown bear genomes …