A molecular switch between mammalian MLL complexes dictates response to Menin–MLL inhibition

…, AA Soshnev, L Gates, MC Beytagh, D Cheon… - Cancer discovery, 2023 - AACR
Menin–MLL inhibitors silence a canonical HOX - and MEIS1 -dependent oncogenic gene
expression program in leukemia. We discovered a parallel, noncanonical transcriptional …

Calcium-permeable AMPA receptors govern PV neuron feature selectivity

…, SH Park, N Limjunyawong, Z Yang, D Cheon… - bioRxiv, 2023 - biorxiv.org
The brain helps us survive by forming internal representations of the external world1,2.
Excitatory cortical neurons are often precisely tuned to specific external stimuli3,4. However, …

Design and simulated performance of calorimetry systems for the ECCE detector at the electron ion collider

…, R Capobianco, WC Chang, Y Cheon… - Nuclear Instruments and …, 2023 - Elsevier
We describe the design and performance the calorimeter systems used in the ECCE detector
to achieve the overall performance specifications cost-effectively with careful consideration …

Detector requirements and simulation results for the EIC exclusive, diffractive and tagging physics program using the ECCE detector concept

…, R Capobianco, WC Chang, Y Cheon… - Nuclear Instruments and …, 2023 - Elsevier
This article presents a collection of simulation studies using the ECCE detector concept in
the context of the EIC’s exclusive, diffractive, and tagging physics program, which aims to …

Search for e→ τ Charged Lepton Flavor Violation at the EIC with the ECCE Detector

…, R Capobianco, WC Chang, Y Cheon… - Nuclear Instruments and …, 2023 - Elsevier
The recently approved Electron-Ion Collider (EIC) will provide a unique new opportunity for
searches of charged lepton flavor violation (CLFV) and other new physics scenarios. In …

Design of the ECCE detector for the Electron Ion Collider

…, R Capobianco, WC Chang, Y Cheon… - arXiv preprint arXiv …, 2022 - arxiv.org
The EIC Comprehensive Chromodynamics Experiment (ECCE) detector has been designed
to address the full scope of the proposed Electron Ion Collider (EIC) physics program as …

Scientific computing plan for the ECCE detector at the Electron Ion Collider

…, R Capobianco, WC Chang, Y Cheon… - Nuclear Instruments and …, 2023 - Elsevier
The Electron Ion Collider (EIC) is the next generation of precision QCD facility to be built at
Brookhaven National Laboratory in conjunction with Thomas Jefferson National Laboratory. …

AI-assisted optimization of the ECCE tracking system at the Electron Ion Collider

…, R Capobianco, WC Chang, Y Cheon… - Nuclear Instruments and …, 2023 - Elsevier
The Electron-Ion Collider (EIC) is a cutting-edge accelerator facility that will study the nature
of the “glue” that binds the building blocks of the visible matter in the universe. The proposed …

Exclusive J/ψ detection and physics with ECCE

…, R Capobianco, WC Chang, Y Cheon… - Nuclear Instruments and …, 2023 - Elsevier
The EIC Comprehensive Chromodynamics Experiment (ECCE) detector has been
recommended as a reference design for the proposed Electron-Ion Collider (EIC) program. This …

Evaluation of longitudinal double-spin asymmetry measurements in semi-inclusive deep-inelastic scattering from the proton for the ECCE detector design

…, R Capobianco, WC Chang, Y Cheon… - Nuclear Instruments and …, 2023 - Elsevier
The evaluation of the measurement of double-spin asymmetries for charge-separated pions
and kaons produced in deep-inelastic scattering from the proton using the ECCE detector …