User profiles for David E. Cook

David Cook

- Verified email at ust.hk - Cited by 3196

David E Cook

- Verified email at ksu.edu - Cited by 2283

Copy Number Variation of Multiple Genes at Rhg1 Mediates Nematode Resistance in Soybean

DE Cook, TG Lee, X Guo, S Melito, K Wang… - science, 2012 - science.org
The rhg1-b allele of soybean is widely used for resistance against soybean cyst nematode (SCN),
the most economically damaging pathogen of soybeans in the United States. Gene …

Understanding plant immunity as a surveillance system to detect invasion

DE Cook, CH Mesarich… - Annual review of …, 2015 - annualreviews.org
Various conceptual models to describe the plant immune system have been presented. The
most recent paradigm to gain wide acceptance in the field is often referred to as the zigzag …

Distinct Copy Number, Coding Sequence, and Locus Methylation Patterns Underlie Rhg1-Mediated Soybean Resistance to Soybean Cyst Nematode

DE Cook, AM Bayless, K Wang, X Guo, Q Song… - Plant …, 2014 - academic.oup.com
Copy number variation of kilobase-scale genomic DNA segments, beyond presence/absence
polymorphisms, can be an important driver of adaptive traits. Resistance to Heterodera …

[PDF][PDF] The contribution of DNA repair pathways to genome editing and evolution in filamentous pathogens

J Huang, DE Cook - FEMS Microbiology Reviews, 2022 - academic.oup.com
DNA double-strand breaks require repair or risk corrupting the language of life. To ensure
genome integrity and viability, multiple DNA double-strand break repair pathways function in …

Mind the gap; seven reasons to close fragmented genome assemblies

…, MF Seidl, X Shi-Kunne, DE Cook… - Fungal Genetics and …, 2016 - Elsevier
Like other domains of life, research into the biology of filamentous microbes has greatly
benefited from the advent of whole-genome sequencing. Next-generation sequencing (NGS) …

[HTML][HTML] Histone modification dynamics at H3K27 are associated with altered transcription of in planta induced genes in Magnaporthe oryzae

W Zhang, J Huang, DE Cook - PLoS genetics, 2021 - journals.plos.org
Transcriptional dynamic in response to environmental and developmental cues are fundamental
to biology, yet many mechanistic aspects are poorly understood. One such example is …

[HTML][HTML] CRISPR-Cas12a induced DNA double-strand breaks are repaired by multiple pathways with different mutation profiles in Magnaporthe oryzae

…, W Zhang, T Suelter, B Valent, DE Cook - Nature …, 2022 - nature.com
CRISPR-Cas mediated genome engineering has revolutionized functional genomics. However,
understanding of DNA repair following Cas-mediated DNA cleavage remains incomplete…

Long-read annotation: automated eukaryotic genome annotation based on long-read cDNA sequencing

DE Cook, JE Valle-Inclan, A Pajoro… - Plant …, 2019 - academic.oup.com
Single-molecule full-length complementary DNA (cDNA) sequencing can aid genome
annotation by revealing transcript structure and alternative splice forms, yet current annotation …

Effect of dietary 2-mercaptoethanol on the life span, immune system, tumor incidence and lipid peroxidation damage in spleen lymphocytes of aging BC3F1 mice

ML Heidrick, LC Hendricks, DE Cook - Mechanisms of ageing and …, 1984 - Elsevier
The age-related decline in immune function, which is though to be responsible for the increased
incidence with age of certain diseases, including cancer, has been attributed primarily …

A unique chromatin profile defines adaptive genomic regions in a fungal plant pathogen

DE Cook, HM Kramer, DE Torres, MF Seidl… - Elife, 2020 - elifesciences.org
Genomes store information at scales beyond the linear nucleotide sequence, which impacts
genome function at the level of an individual, while influences on populations and long-term …