Background Psilocybin may have antidepressant properties, but direct comparisons between
psilocybin and established treatments for depression are lacking. Methods In a phase 2, …

Psychedelic drugs have a long history of use in healing ceremonies, but despite renewed
interest in their therapeutic potential, we continue to know very little about how they work in the …

Background Psilocybin is a serotonin receptor agonist that occurs naturally in some mushroom
species. Recent studies have assessed the therapeutic potential of psilocybin for various …

For several decades, addiction has come to be viewed as a disorder of the dopamine
neurotransmitter system; however, this view has not led to new treatments. In this Opinion article, …

Objective To conduct a systematic review of modern‐era (post‐millennium) clinical studies
assessing the therapeutic effects of serotonergic psychedelics drugs for mental health …

After a legally mandated, decades-long global arrest of research on psychedelic drugs,
investigation of psychedelics in the context of psychiatric disorders is yielding exciting results. …

Psychedelics have attracted medical interest, but their effects on human brain function are
incompletely understood. In a comprehensive, within-subjects, placebo-controlled design, we …

Psychedelic drugs are making waves as modern trials support their therapeutic potential and
various media continue to pique public interest. In this opinion piece, we draw attention to a …

Background: In the past few years, the issue of ‘microdosing’ psychedelics has been openly
discussed in the public arena where claims have been made about their positive effect on …

Psilocybin therapy shows antidepressant potential, but its therapeutic actions are not well
understood. We assessed the subacute impact of psilocybin on brain function in two clinical …