The newly identified severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes
COVID-19, a pandemic respiratory disease. Moreover, thromboembolic events throughout …

Members of the miR-34 family are induced by the tumor suppressor p53 and are known to
inhibit epithelial-to-mesenchymal transition (EMT) and therefore presumably suppress the …

Infection by the new corona virus strain SARS-CoV-2 and its related syndrome COVID-19 has
been associated with more than two million deaths worldwide. Patients of higher age and …

Background and aims: This prospective trial was designed to compare the performance
characteristics of five different screening tests in parallel for the detection of advanced colonic …

It is now well known that non-coding RNAs (ncRNAs), rather than protein-coding transcripts,
are the preponderant RNA transcripts. NcRNAs, particularly microRNAs (miRNAs), long non-…

Among the cytokines linked to inflammation-associated cancer, interleukin (IL)-6 drives
many of the cancer "hallmarks" through downstream activation of the gp130/STAT3 signaling …

COVID-19-induced "acute respiratory distress syndrome" (ARDS) is associated with prolonged
respiratory failure and high mortality, but the mechanistic basis of lung injury remains …

Loss of p53 is considered to allow progression of colorectal tumors from the adenoma to the
carcinoma stage. Using mice with an intestinal epithelial cell (IEC)-specific p53 deletion, we …

In colon cancer, CD133 has recently been used to enrich for a subset of tumour cells with
tumour‐initiating capabilities and was therefore suggested to mark colon cancer stem cells. …

CD133, CD44, and CD166 are cell surface markers that have recently been associated with
colorectal cancer stem cells. As which of these markers has the greatest impact on patient …