The ubiquitin-dependent degradation of a test protein β-galactosidase (βgal) is preceded by
ubiquitination of βgal. The many (from 1 to more than 20) ubiquitin moieties attached to a …

Military medical facilities treating patients injured in Iraq and Afghanistan have identified a
large number of multidrug-resistant (MDR) Acinetobacter baumannii isolates. In order to …

RNA molecules fold into characteristic secondary and tertiary structures that account for their
diverse functional activities. Many of these RNA structures are assembled from a collection …

The degradation of many proteins requires their prior attachment to ubiquitin. Proteolytic
substrates are characteristically multiubiquitinated through the formation of ubiquitin-ubiquitin …

We describe a new technology, the Ibis T5000, for the identification of pathogens in clinical
and environmental samples. The Ibis T5000 couples nucleic acid amplification to high-…

The phosphorothioate oligonucleotide T2G4T2 was identified as an inhibitor of HIV infection
in vitro by combinatorial screening of a library of phosphorothioate oligonucleotides that …

A new algorithm called RNAMotif containing RNA structure and sequence constraints and a
thermodynamic scoring system was used to search for intrinsic rho-independent terminators …

Many procedures used in assisted reproductive technologies (ART) to treat human infertility
entail culture of preimplantation embryos. Moreover, there is an increasing trend to culture …

High-throughput screening of in-house compound libraries led to the discovery of a novel
antibacterial agent, compound 1 (MIC: 12−25 μM against S. pyogenes). In an effort to improve …

Efforts have been made to improve the biological stability of phosphodiester (PO) oligonucleotides
by the addition of various modifications to either the 3', 5′ or both the 3’ and 5’ ends …