Malaria elimination strategies require surveillance of the parasite population for genetic
changes that demand a public health response, such as new forms of drug resistance 1 , 2 . …

We report a genome-wide association (GWA) study of severe malaria in The Gambia. The
initial GWA scan included 2,500 children genotyped on the Affymetrix 500K GeneChip, and a …

High mutation rate in mammalian mitochondrial DNA generates a highly divergent pool of
alleles even within species that have dispersed and expanded in size recently. Phylogenetic …

Haemoglobin C (HbC; β6Glu → Lys) is common in malarious areas of West Africa, especially
in Burkina Faso 1 , 2 . Conclusive evidence exists on the protective role against severe …

The variation of 77 biallelic sites located in the nonrecombining portion of the Y chromosome
was examined in 608 male subjects from 22 African populations. This survey revealed a …

The comparison of malaria indicators among populations that have different genetic backgrounds
and are uniformly exposed to the same parasite strains is one approach to the study of …

We present a second-order Godunov algorithm to solve time-dependent hyperbolic systems
of conservation laws on irregular domains. Our approach is based on a formally consistent …

INTRODUCTION Malaria parasites cause human disease by invading and replicating inside
red blood cells. In the case of Plasmodium falciparum, this can lead to severe forms of …

Previous interethnic comparative studies on the susceptibility to malaria performed in West
Africa showed that Fulani are more resistant to Plasmodium falciparum malaria than are …

We compared malaria indicators among sympatric groups to study human heterogeneities in
the response to Plasmodium falciparum malaria infection. Four cross-sectional surveys and …