User profiles for David Perrais
David PerraisResearch Director at CNRS, IINS University of Bordeaux Verified email at u-bordeaux.fr Cited by 6144 |
[HTML][HTML] A high precision survey of the molecular dynamics of mammalian clathrin-mediated endocytosis
Dual colour total internal reflection fluorescence microscopy is a powerful tool for decoding
the molecular dynamics of clathrin-mediated endocytosis (CME). Typically, the recruitment of …
the molecular dynamics of clathrin-mediated endocytosis (CME). Typically, the recruitment of …
[HTML][HTML] Coupling between clathrin-coated-pit invagination, cortactin recruitment, and membrane scission observed in live cells
CJ Merrifield, D Perrais, D Zenisek - Cell, 2005 - cell.com
During clathrin-mediated endocytosis, membrane scission marks the isolation of a cargo-laden
clathrin-coated pit (CCP) from the cell exterior. Here we used live-cell imaging of a pH-…
clathrin-coated pit (CCP) from the cell exterior. Here we used live-cell imaging of a pH-…
Shiga toxin induces tubular membrane invaginations for its uptake into cells
…, D Tenza, MRE Aly, V Fraisier, JC Florent, D Perrais… - Nature, 2007 - nature.com
Clathrin seems to be dispensable for some endocytic processes and, in several instances,
no cytosolic coat protein complexes could be detected at sites of membrane invagination. …
no cytosolic coat protein complexes could be detected at sites of membrane invagination. …
Brain extracellular matrix affects AMPA receptor lateral mobility and short-term synaptic plasticity
Many synapses in the mature CNS are wrapped by a dense extracellular matrix (ECM). Using
single-particle tracking and fluorescence recovery after photobleaching, we found that this …
single-particle tracking and fluorescence recovery after photobleaching, we found that this …
Secretory granules are recaptured largely intact after stimulated exocytosis in cultured endocrine cells
JW Taraska, D Perrais… - Proceedings of the …, 2003 - National Acad Sciences
Classical cell biology teaches that exocytosis causes the membrane of exocytic vesicles to
disperse into the cell surface and that a cell must later retrieve by molecular sorting whatever …
disperse into the cell surface and that a cell must later retrieve by molecular sorting whatever …
[HTML][HTML] SHANK3 mutations identified in autism lead to modification of dendritic spine morphology via an actin-dependent mechanism
CM Durand, J Perroy, F Loll, D Perrais, L Fagni… - Molecular …, 2012 - nature.com
Genetic mutations of SHANK3 have been reported in patients with intellectual disability,
autism spectrum disorder (ASD) and schizophrenia. At the synapse, Shank3/ProSAP2 is a …
autism spectrum disorder (ASD) and schizophrenia. At the synapse, Shank3/ProSAP2 is a …
pHuji, a pH-sensitive red fluorescent protein for imaging of exo-and endocytosis
Fluorescent proteins with pH-sensitive fluorescence are valuable tools for the imaging of
exocytosis and endocytosis. The Aequorea green fluorescent protein mutant superecliptic …
exocytosis and endocytosis. The Aequorea green fluorescent protein mutant superecliptic …
Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia
…, C Desnos, E Formstecher, F Darchen, D Perrais… - Journal of Cell …, 2013 - rupress.org
Remodeling of the extracellular matrix by carcinoma cells during metastatic dissemination
requires formation of actin-based protrusions of the plasma membrane called invadopodia, …
requires formation of actin-based protrusions of the plasma membrane called invadopodia, …
Effect of zolpidem on miniature IPSCs and occupancy of postsynaptic GABAA receptors in central synapses
D Perrais, N Ropert - Journal of Neuroscience, 1999 - Soc Neuroscience
GABA A -mediated miniature IPSCs (mIPSCs) were recorded from layer V pyramidal neurons
of the visual cortex using whole-cell patch-clamp recording in rat brain slices. At room …
of the visual cortex using whole-cell patch-clamp recording in rat brain slices. At room …
GluR7 is an essential subunit of presynaptic kainate autoreceptors at hippocampal mossy fiber synapses
PS Pinheiro, D Perrais, F Coussen… - Proceedings of the …, 2007 - National Acad Sciences
Presynaptic ionotropic glutamate receptors are emerging as key players in the regulation of
synaptic transmission. Here we identify GluR7, a kainate receptor (KAR) subunit with no …
synaptic transmission. Here we identify GluR7, a kainate receptor (KAR) subunit with no …