User profiles for David Qian

David Z. Qian

- Verified email at ohsu.edu - Cited by 6068

David D Qian

- Verified email at polyu.edu.hk - Cited by 4511

David Qian, MD, PhD

- Verified email at mdanderson.org - Cited by 1708

Investigating the relationship between vocabulary knowledge and academic reading performance: An assessment perspective

DD Qian - Language learning, 2002 - Wiley Online Library
… Correspondence concerning this article may be addressed to David D. Qian, Asian
Centre for Language Assessment Research, Department of English, Hong Kong Polytechnic …

Assessing the roles of depth and breadth of vocabulary knowledge in reading comprehension

D Qian - Canadian modern language review, 1999 - utpjournals.press
This empirical study explored the relationships between depth and breadth of vocabulary
knowledge and reading comprehension in English as a second language (ESL). Using …

Digoxin and other cardiac glycosides inhibit HIF-1α synthesis and block tumor growth

H Zhang, DZ Qian, YS Tan, KA Lee… - Proceedings of the …, 2008 - National Acad Sciences
A library of drugs that are in clinical trials or use was screened for inhibitors of hypoxia-inducible
factor 1 (HIF-1). Twenty drugs inhibited HIF-1-dependent gene transcription by >88% at …

Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes

…, X Xiao, Y Li, J Byun, A Dunning, KA Pooley, DC Qian… - Nature …, 2017 - nature.com
Although several lung cancer susceptibility loci have been identified, much of the heritability
for lung cancer remains unexplained. Here 14,803 cases and 12,262 controls of European …

Acriflavine inhibits HIF-1 dimerization, tumor growth, and vascularization

KA Lee, H Zhang, DZ Qian, S Rey… - Proceedings of the …, 2009 - National Acad Sciences
HIF-1 is a heterodimeric transcription factor that mediates adaptive responses to hypoxia
and plays critical roles in cancer progression. Using a cell-based screening assay we have …

Evaluation of an in-depth vocabulary knowledge measure for assessing reading performance

DD Qian, M Schedl - Language Testing, 2004 - journals.sagepub.com
The central purpose of this study was to empirically evaluate an in-depth vocabulary knowledge
measure in the context of developing the new TOEFL test. The study was carried out …

Identifying phenotype-associated subpopulations by integrating bulk and single-cell sequencing data

D Sun, X Guan, AE Moran, LY Wu, DZ Qian… - Nature …, 2022 - nature.com
Single-cell RNA sequencing (scRNA-seq) distinguishes cell types, states and lineages within
the context of heterogeneous tissues. However, current single-cell data cannot directly link …

Tubulin-targeting chemotherapy impairs androgen receptor activity in prostate cancer

ML Zhu, CM Horbinski, M Garzotto, DZ Qian, TM Beer… - Cancer research, 2010 - AACR
Recent insights into the regulation of the androgen receptor (AR) activity led to novel
therapeutic targeting of AR function in prostate cancer patients. Docetaxel is an approved …

Class II histone deacetylases are associated with VHL-independent regulation of hypoxia-inducible factor 1α

DZ Qian, SK Kachhap, SJ Collis, HMW Verheul… - Cancer research, 2006 - AACR
Hypoxia-inducible factor 1α (HIF-1α) plays a critical role in transcriptional gene activation
involved in tumor angiogenesis. A novel class of agents, the histone deacetylase (HDAC) …

Anthracycline chemotherapy inhibits HIF-1 transcriptional activity and tumor-induced mobilization of circulating angiogenic cells

KA Lee, DZ Qian, S Rey, H Wei… - Proceedings of the …, 2009 - National Acad Sciences
Using a cell-based reporter gene assay, we screened a library of drugs in clinical use and
identified the anthracycline chemotherapeutic agents doxorubicin and daunorubicin as potent …