• We investigated the effectiveness of two brief psychotherapies, interpersonal psychotherapy
and cognitive behavior therapy, for the treatment of outpatients with major depressive …

Objective: The authors investigated patient characteristics predictive of treatment response
in the National Institute of Mental Health (NIMH) Treatment of Depression Collaborative …

• We studied the course of depressive symptoms during an 18-month naturalistic follow-up
period for outpatients with Major Depressive Disorder treated in the National Institute of …

In the NIMH Treatment of Depression Collaborative Research Program (TDCRP), 250
depressed outpatients were randomly assigned to interpersonal psychotherapy, cognitive–…

Cellular metabolism regulates immune cell activation, differentiation and effector functions,
but current metabolic approaches lack single-cell resolution and simultaneous …

Ductal carcinoma in situ (DCIS) is a pre-invasive lesion that is thought to be a precursor to
invasive breast cancer (IBC). To understand the changes in the tumor microenvironment (TME…

B cells are capable of a wide range of effector functions including antibody secretion, antigen
presentation, cytokine production, and generation of immunological memory. A consistent …

The frequency of DSM-III, Axis II personality disorders and their relationship to selected
demographic and clinical characteristics were investigated in a sample of 249 outpatients with …

Allergen-specific immunoglobulin E (IgE) antibodies mediate pathology in diseases such as
allergic rhinitis and food allergy. Memory B cells (MBCs) contribute to circulating IgE by …

Regulatory B cells (Bregs) suppress immune responses through the secretion of interleukin-10
(IL-10). This immunomodulatory capacity holds therapeutic potential, yet a definitional …