User profiles for David R. Benavides

David R. Benavides, MD, Ph.D.

Assistant Professor of Neurology at University of Maryland School of Medicine
Verified email at som.umaryland.edu
Cited by 2031

Autoimmune encephalitis: proposed best practice recommendations for diagnosis and acute management

…, S Irani, B Ances, DR Benavides… - Journal of Neurology …, 2021 - jnnp.bmj.com
The objective of this paper is to evaluate available evidence for each step in autoimmune
encephalitis management and provide expert opinion when evidence is lacking. The paper …

Cyclin-dependent kinase 5 governs learning and synaptic plasticity via control of NMDAR degradation

AH Hawasli, DR Benavides, C Nguyen, JW Kansy… - Nature …, 2007 - nature.com
Learning is accompanied by modulation of postsynaptic signal transduction pathways in
neurons. Although the neuronal protein kinase cyclin-dependent kinase 5 (Cdk5) has been …

Association of autoimmune encephalitis with combined immune checkpoint inhibitor treatment for metastatic cancer

TJ Williams, DR Benavides, KA Patrice… - JAMA …, 2016 - jamanetwork.com
Importance Paraneoplastic encephalitides usually precede a diagnosis of cancer and are
often refractory to immunosuppressive therapy. Conversely, autoimmune encephalitides are …

Predictors of outcome in acute encephalitis

…, M Motta, AO Asemota, HL Kirsch, DR Benavides… - Neurology, 2013 - AAN Enterprises
Objective: To investigate predictors of outcome in patients with all-cause encephalitis receiving
care in the intensive care unit. Methods: A retrospective analysis of encephalitis cases at …

Phase I/II multicenter ketogenic diet study for adult superrefractory status epilepticus

…, AL Hartman, JC Probasco, DR Benavides… - Neurology, 2017 - AAN Enterprises
Objective: To investigate the feasibility, safety, and efficacy of a ketogenic diet (KD) for
superrefractory status epilepticus (SRSE) in adults. Methods: We performed a prospective …

Cdk5 is essential for adult hippocampal neurogenesis

DC Lagace, DR Benavides, JW Kansy… - Proceedings of the …, 2008 - National Acad Sciences
The molecular factors regulating adult neurogenesis must be understood to harness the
therapeutic potential of neuronal stem cells. Although cyclin-dependent kinase 5 (Cdk5) plays a …

Autoimmune encephalitis: proposed recommendations for symptomatic and long-term management

…, SR Irani, B Ances, DR Benavides… - Journal of Neurology …, 2021 - jnnp.bmj.com
The objective of this paper is to evaluate available evidence for each step in autoimmune
encephalitis management and provide expert opinion when evidence is lacking. The paper …

Autoimmune encephalitis and its relation to infection

A Venkatesan, DR Benavides - Current neurology and neuroscience …, 2015 - Springer
Encephalitis, an inflammatory condition of the brain that results in substantial morbidity and
mortality, has numerous causes. Over the past decade, it has become increasingly …

The role of ventral striatal cAMP signaling in stress-induced behaviors

…, K Hayashi, A Hernández, DR Benavides… - Nature …, 2015 - nature.com
The cAMP and cAMP-dependent protein kinase A (PKA) signaling cascade is a ubiquitous
pathway acting downstream of multiple neuromodulators. We found that the phosphorylation …

Cdk5 modulates cocaine reward, motivation, and striatal neuron excitability

DR Benavides, JJ Quinn, P Zhong… - Journal of …, 2007 - Soc Neuroscience
Cyclin-dependent kinase 5 (Cdk5) regulates dopamine neurotransmission and has been
suggested to serve as a homeostatic target of chronic psychostimulant exposure. To study the …