Genome-wide association studies (GWAS) have identified >250 loci for body mass index (BMI),
implicating pathways related to neuronal biology. Most GWAS loci represent clusters of …

Body-fat distribution is a risk factor for adverse cardiovascular health consequences. We
analyzed the association of body-fat distribution, assessed by waist-to-hip ratio adjusted for …

In the version of this article originally published, one of the two authors with the name Wei
Zhao was omitted from the author list and the affiliations for both authors were assigned to the …

… Crosslin, Gabriel Cuellar-Partida, Angela D’Eustacchio, John Danesh, Gail Davies, Paul IW
Bakker, Mark CH Groot, Renée Mutsert, Ian J. Deary, George Dedoussis, Ellen W. Demerath …

Candidate gene and genome-wide association studies (GWAS) have identified genetic variants
that modulate risk for human disease; many of these associations require further study to …

… V Turcot, Y Lu, HM Highland, C Schurmann, AE Justice, RS Fine, JP Bradfield, T Esko, A
Giri, M Graff, X Guo, AE Hendricks, T Karaderi, A Lempradl, AE Locke, A Mahajan, E Marouli …

Many modern human genomes retain DNA inherited from interbreeding with archaic
hominins, such as Neandertals, yet the influence of this admixture on human traits is largely …

We describe here the design and initial implementation of the eMERGE‐PGx project.
eMERGE‐PGx, a partnership of the Electronic Medical Records and Genomics Network and the …

Background Statin treatment and variants in the gene encoding HMG-CoA reductase are
associated with reductions in both the concentration of LDL cholesterol and the risk of coronary …

Genetic variation can affect drug response in multiple ways, although it remains unclear how
rare genetic variants affect drug response. The electronic Medical Records and Genomics (…